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APNewsBreak: SC man sues eye centers after Lasik

A federal lawsuit filed Wednesday in South Carolina accuses eye clinics across the country of performing surgeries on patients with pre-existing conditions that should have excluded them as candidates, causing those patients to suffer post-operative problems.Practitioners in 30 TLC LASIK...

Synergetics 2Q profit doubles on cost cutting

Surgical equipment maker Synergetics USA Inc. said Wednesday that its profit more than doubled in its fiscal second quarter as it cut back on sales and marketing spending.In the quarter ended Jan. 31, the company's profit rose to $877,000, or 4 cents per share, from $389,000, or 2 cents per...

Report questions excluding gays from some studies

A small but significant portion of medical studies exclude gays from participating, sometimes without an apparent scientific reason, several cancer researchers say.In a letter in Thursday's New England Journal of Medicine, three scientists from the Fox Chase Cancer Center in Philadelphia cite...

SurModics licenses technology from ForSight Labs

SurModics Inc. said Wednesday that it licensed ophthalmology technology from ForSight Labs LLC for an undisclosed sum.The medical technology company said the deal includes an upfront license payment, milestone payments, and royalties. SurModics said the deal does not include ForSight's I-vation...

Research monkey deaths prompt calls for crackdown

Workers at a Nevada research lab were checking on a primate room when they came across a ghastly sight: Thirty dead monkeys were essentially cooked alive after someone left the heater on. Two others were near death and had to be euthanized.At a lab run by the same company, a monkey died last...

Disabling Skp2 gene helps shut down cancer growth

(University of Texas M. D. Anderson Cancer Center) Increased understanding of the Skp2 gene and its relation to cellular senescence may lead to the development of novel agents that can suppress tumor development in common types of cancer, researchers from the University of Texas M....

DiagnoCure reports deeper $3.8-million loss in Q1; CFO to leave his role

DiagnoCure Inc. (TSX:CUR) says its losses deepened to $3.8 million in its first quarter as the life-sciences firm reworked the structure of the company and announced the exit of its chief financial officer.The Quebec-based company reported a loss of nine cents per share for the period ended...

Modified home video game shows promise for improving hand function in teens with cerebral palsy

(Rutgers University) Rutgers engineers have modified a popular home video game system to help teenagers with cerebral palsy improve their hand functions. In a pilot trial conducted by the Indiana University School of Medicine, the system improved the teens' abilities to perform a...

J&J CEO Weldon gets 11 pct 2009 raise, to $25.6M

The Associated Press finds Johnson & Johnson's chief executive got an 11 percent raise in 2009, even though the health giant saw revenue fall for the first time since the Depression.Bill Weldon received 2009 compensation valued at $25.6 million, based on figures in a regulatory filing.The New...

Teva and Merck agree on generic Temodar launch

Teva Pharmaceutical Industries Ltd. said Wednesday it agreed to hold off on launching a generic version of Merck & Co.'s cancer drug Temodar until a federal appeals court weighs in on the drug's patent.Instead of launching its generic version of Temodar now, Teva said it will begin selling its...

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Research Exchange

Publishing Data That Conform to the MIQE Guidelines

Jan 22

Minimum information for publication of Quantitative Real-Time PCR Experiments (MIQE) guidelines help researchers design qPCR experiments.

Calibration Free Analysis to Measure the Concentration of Active Proteins

Nov 23 2009

An SPR-based method, Calibration Free Concentration Analysis can be used to accurately determine the concentration of active protein in a sample, relating to the specific binding activity of the protein, and without the need for a standard.

Advances in EMCCD Technology: Making Imaging Less Arbitrary

Advances in EMCCD Technology: Making Imaging Less Arbitrary

Nov 16 2009

Recent advances in EMCCD technology have solved the problem of non-standardized measurement units by using the photoelectron to standardize imaging experiments.

10 Tips for Successful Sample Concentration and Buffer Exchange

10 Tips for Successful Sample Concentration and Buffer Exchange

Nov 6 2009

Centrifugal devices with ultrafiltration (UF) membrane can solve common problems researchers face when working with proteins.

Advantages of Monolithic Laser Combiner Technology in Confocal Microscopy Systems

Jan 6

Fluorescence microscopy techniques require a reliable light source at the desired wavelength or wavelengths, with minimal downtime for maintenance and alignment. Lasers are a popular light source, although the alignment and upkeep of laser combiners is a time-consuming prospect for many users.

Size-Exclusion Chromatography for Purification of Biomolecules

Dec 2 2009

Size-exclusion chromatography (SEC) is a popular method to separate biomolecules based on their size. Primarily, it is applied to the separation of biopolymers such as proteins and nucleic acids, i.e. water-soluble polymers.

Improving Separation During Electrophoresis

Dec 2 2009

SeparateIT gels represent a novel gel matrix for DNA electrophoresis. Gel polymers are arranged in a conceptually different way, in accordance with a new theoretical model of gel electrophoresis.

Improving Quality of ELISA

Dec 2 2009

Using ready-to-use ELISA kits from manufacturers is easy and convenient. Sometimes however, home-made ELISA is required because there is no kit available with the right antibodies or the characteristics of the available kits such as their limits of detection are not appropriate.

Using the Tecan Genesis Workstation to Automate a Cytometric Bead Array (CBA) Immunoassay

Mar 11

The poster describe the process involved in automating a Cytometric Bead Array (CBA) immunoassay developed to measure relative concentrations of serum antibodies against Tetanus (TT), Sperm Whale Myoglobin (SWM) and Keyhole Limpet Hemocyanin (KLH) in KLH-immunized volunteers.

Ensuring Quality in Assays Performed with Automated Liquid Handlers

Feb 2

The focus of this presentation is to highlight the need of ensuring quality in important assays performed with automated liquid handlers. Nearly all assays performed within a laboratory are volume-dependent. In turn, all concentrations of biological and chemical components in these assays, as well as the associated dilution protocols, are volume-dependent. Because analyte concentration is volume-dependent, an assay’s results might be falsely interpreted if liquid handler variability and inaccuracies are unknown or if the system(s) go unchecked for a long period.

Inkjet System for Protein Crystallography

Feb 1

X-ray crystallography is used routinely by scientists to obtain the three dimensional structure of a biological molecule of interest.Such information can be used to determine how a pharmaceutical interacts with a protein target and what changes might improve functionality. However, the crystallization of macromolecules still remains a serious hindrance in structural determination despite impressive advances in screening methods and technologies.

Attention Deficit & Hyperactivity in a Drosophila Memory Mutant

Attention Deficit & Hyperactivity in a Drosophila Memory Mutant

Nov 9 2009

Action selection is modulated by external stimuli either directly or via memory retrieval. In a constantly changing environment, animals have evolved attention-like processes to effectively filter the incoming sensory stream. These attention-like processes, in turn, are modulated by memory. The neurobiological nature of how attention, action selection and memory are inter-connected is unknown. We describe here new phenotypes of the memory mutant radish in the fruit fly Drosophila.

Relationship between multiple sources of perceived social support and psychological and academic adjustment in early adolescence: comparisons across gender.

Mar 8

The current study investigated gender differences in the relationship between sources of perceived support (parent, teacher, classmate, friend, school) and psychological and academic adjustment in a sample of 636 (49% male) middle school students. Longitudinal data were...

Involvement of ceramide in ischemic tolerance induced by preconditioning with sublethal oxygen-glucose deprivation in primary cultured cortical neurons of rats.

Feb 25

The complex molecular cascades of ischemic tolerance in brain cells remain unclear. Recently, sphingolipid-related metabolite ceramide has been implicated as a second messenger in many biological functions, including neuronal survival and death. The present study, therefore,...

Social intelligence and academic achievement as predictors of adolescent popularity.

Feb 24

This study compared the effects of social intelligence and cognitive intelligence, as measured by academic achievement, on adolescent popularity in two school contexts. A distinction was made between sociometric popularity, a measure of acceptance, and perceived popularity, a...

Prokariotic Cell Collection in Denmark

Nov 6 2009

I would like to know about a prokariotic cell collection in Denmark. Is there a cell bank in this country? I need a Lactobacillus strain for a fermentation assay and this information about the bank is very helpful for me.

Request for Entries

Oct 16 2009

Ask the Experts is your chance to get the answers to questions on applications, materials, methods, processes, and technologies. Email you question to bst_web@advantagemedia.com, and the editors of Bioscience Technology will find an appropriate expert to answer it. Watch this space in the future to see the questions your colleagues are posting.          

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Video:

Neuroscience Diseases of The Brain and How The Mind Emerges

Neuroscience Diseases of The Brain and How The Mind Emerges

Nov 8 2009

Dennis Choi, director of Emory Universitys Neuroscience Center, is renowned for his groundbreaking research on brain and spinal cord injury.

Podcasts:

Allen Institute for Brain Research

Allen Institute for Brain Research

Oct 14 2009

Discussed in this interview are both the mouse brain project and the human cortex project with an emphasis on the importance of these projects to neuroscience research.