Bioscience Technology Online - PubGet

Carving the CAR.

Fri, 30 Jul 2010 09:46:44 GMT

Winners and losers and oncolytic adenoviruses: who should be down in the mouth?

Fri, 30 Jul 2010 09:46:40 GMT

Mobile genetic elements of Staphylococcus aureus.

Fri, 30 Jul 2010 09:46:36 GMT

Bacteria such as Staphylococcus aureus are successful as commensal organisms or pathogens in part because they adapt rapidly to selective pressures imparted by the human host. Mobile genetic elements (MGEs) play a central role in this adaptation process and are...

Interferon-Gamma Release Assay in the Ascites: Early Hint for Diagnosis of Abdominal Tuberculosis

Thu, 29 Jul 2010 21:46:54 GMT

We report on a 20-year-old woman with abdominal tuberculosis. Standard microbiological examination of ascites showed no acid-fast bacilli (AFB), and analysis for the Mycobacterium tuberculosis (MTB)-complex DNA by PCR was negative. However, the interferon-γ release assay (IGRA)...

Coverage and Predictors of Adherence to Influenza Vaccination among Spanish Children and Adults with Asthma

Thu, 29 Jul 2010 21:46:41 GMT

Background Influenza infections are frequently implicated in the exacerbation of asthma. The aim of this study was to assess vaccination coverage among Spanish children and adults with asthma and to describe the factors associated (predictors) with vaccination, using data from...

Persistent Helicobacter canis Bacteremia in a Patient with Gastric Lymphoma

Thu, 29 Jul 2010 21:46:37 GMT

A 78-year-old man with gastric diffuse large B cell lymphoma presented with persistent Helicobacter canis bacteremia while receiving chemotherapy. An examination of his medical history revealed a close exposure to dogs. The patient recovered after 4 weeks of antibiotic therapy....

Management of Hepatitis B Virus Reactivation in Patients with Hematological Malignancies Treated with Chemotherapy

Thu, 29 Jul 2010 21:46:23 GMT

Introduction Hepatitis B virus (HBV) reactivation is a major cause of morbidity and mortality in patients with hematological malignancies who receive cytotoxic chemotherapy. We have therefore carried out a prospective observational study out to assess the incidence, prevalence,...

Comment on "Patterns of Diversity in Marine Phytoplankton"

Thu, 29 Jul 2010 18:46:26 GMT

Barton et al. (Reports, 19 March 2010, p. 1509) argued that stable conditions enable neutral coexistence of many phytoplankton species in the tropical oceans, whereas seasonal variation causes low biodiversity in subpolar oceans. However, their model prediction is not robust. A...

Calculation of effective penetration depth in X-ray diffraction for pharmaceutical solids.

Thu, 29 Jul 2010 15:46:22 GMT

The use of the glancing incidence X-ray diffraction configuration to depth profile surface phase transformations is of interest to pharmaceutical scientists. The Parratt equation has been used to depth profile phase changes in pharmaceutical compacts. However,...

Nitric oxide and clustering of metabolic syndrome components in pediatrics

Thu, 29 Jul 2010 13:46:22 GMT

This study was performed to determine the risk factor pattern of the metabolic syndrome (MetS) in association with serum nitric oxide metabolites (NOx) in children and adolescents. The study included 851 children and adolescents, aged 4–19 years. The MetS was defined according...

Defining and measuring ecological specialization

Thu, 29 Jul 2010 10:46:52 GMT

1. Ecological specialization is one of the main concepts in ecology and conservation. However, this concept has become highly context-dependent and is now obscured by the great variability of existing definitions and methods used to characterize ecological specialization. 2....

Oilseed rape crops distort plant–pollinator interactions

Thu, 29 Jul 2010 10:46:48 GMT

1. New incentives at the national and international level frequently lead to substantial structural changes in agricultural landscapes. Subsidizing energy crops, for example, recently fostered a strong increase in the area cultivated with oilseed rape Brassica napus across the...

Long-term changes in the flora of the cereal ecosystem on the Sussex Downs, England, focusing on the years 1968–2005

Thu, 29 Jul 2010 10:46:44 GMT

1. There has been a surge of interest in the effects of modern agriculture on biodiversity but studies of farmland flora have lacked continuity and historical context. Here we present the results of 38 years of annual monitoring of the weed flora of cereal crops on the Sussex...

The introduction of coastal infrastructure as a driver of change in marine environments

Thu, 29 Jul 2010 10:46:40 GMT

1. Coastal landscapes are being transformed as a consequence of the increasing demand for urban infrastructure to sustain commercial, residential and tourist activities. A variety of man-made structures, such as breakwaters, jetties and seawalls have thus become ubiquitous...

Predictability of repeated carnivore attacks on livestock favours reactive use of mitigation measures

Thu, 29 Jul 2010 10:46:35 GMT

1. Predation on livestock is one of the main reasons for low tolerance against large carnivores in many parts of the world. Measures to reduce the conflicts have been developed, but resources for using them are often scarce. If wildlife managers as well as farmers learn more...

Alternative states models provide an effective framework for invasive species control and restoration of native communities

Thu, 29 Jul 2010 10:46:31 GMT

1. Identifying the mechanisms that facilitate invasion is crucial for the design of preventative measures and understanding the invasion process, but not necessarily for the design of effective control strategies. 2. When a novel disturbance is identified as facilitating...

Resource availability and the persistence of seed-eating bird populations in agricultural landscapes : a mechanistic modelling approach

Thu, 29 Jul 2010 10:46:27 GMT

1. Reductions in resource availability, associated with land-use change and agricultural intensification in the UK and Europe, have been linked with the widespread decline of many farmland bird species over recent decades. However, the underlying ecological processes which link...

Single photon emission computed tomography/spiral computed tomography fusion imaging for the diagnosis of bone metastasis in patients with known cancer.

Wed, 28 Jul 2010 01:47:12 GMT

PURPOSE: To evaluate single photon emission computed tomography (SPECT)/spiral computed tomography (CT) fusion imaging for the diagnosis of bone metastasis in patients with known cancer and to compare the diagnostic efficacy of SPECT/CT fusion imaging with that...

Selective arterial embolization of 36 aneurysmal bone cysts of the skeleton with N-2-butyl cyanoacrylate.

Wed, 28 Jul 2010 01:46:58 GMT

BACKGROUND: Aneurysmal bone cyst (ABC) is a lytic benign bone lesion representing about 1% of all primary bone tumors. The lesion causes pain and swelling, which are generally present for less than 3 months. METHODS: From April 2003 to April 2008 36 patients...

Do we really need radiographic assessment for the diagnosis of non-specific heel pain (calcaneal apophysitis) in children?

Wed, 28 Jul 2010 01:46:52 GMT

OBJECTIVE: Non-specific heel pain (calcaneal apophysitis) is a common disorder, particularly in physically active growing children. Foot radiographs are usually obtained as part of the clinical evaluation in routine orthopaedic practice. However, there is still...

Evaluation of anterior talofibular ligament injury with stress radiography, ultrasonography and MR imaging.

Wed, 28 Jul 2010 01:46:48 GMT

OBJECTIVE: The purpose of this study was to clarify the efficacy of stress radiography (stress X-P), ultrasonography (US), and magnetic resonance (MR) imaging in the detection of the anterior talofibular ligament (ATFL) injury. METHODS: Thirty-four patients with...

Review: imaging of groin pain in the athlete.

Wed, 28 Jul 2010 01:46:44 GMT

Chronic groin pain is a common entity in the sporting population and causes considerable morbidity. The differential diagnosis is wide, and this article presents a review of the common causes with particular reference to anatomy, ultrasound and magnetic...

Evidence-based radiology (part 2): Is there sufficient research to support the use of therapeutic injections into the peripheral joints?

Wed, 28 Jul 2010 01:46:39 GMT

INTRODUCTION: This review article addresses the best evidence currently available for the effectiveness of injection therapy for musculoskeletal conditions involving the peripheral joints. The research is presented by anatomical region and areas of controversy...

Early detection of bony alterations in rheumatoid and erosive arthritis of finger joints with high-resolution single photon emission computed tomography, and differentiation b...

Wed, 28 Jul 2010 01:46:35 GMT

OBJECTIVE: To evaluate high-resolution multi-pinhole single photon emission computed tomography (MPH-SPECT) for the detection of bony alterations in early rheumatoid arthritis (ERA), early osteoarthritis (EOA) of the fingers and healthy controls. METHODS: The...

Benefits of molecular pathology in the diagnosis of musculoskeletal disease : Part II of a two-part review: bone tumors and metabolic disorders.

Wed, 28 Jul 2010 01:46:31 GMT

The second part of this review, on the benefits of molecular pathology in the diagnosis disease, focuses on the genetics of bone tumors and metabolic disease. Unlike soft tissue tumors, the number of currently exploitable molecular abnormalities for diagnosing...

Atypical rapid progression of osteoarticular amyloidosis involving the hip in a patient on hemodialysis using polyacrylonitrile membranes.

Wed, 28 Jul 2010 01:46:27 GMT

Amyloidosis related to dialysis is a well-known complication affecting many organ systems, in particular the musculoskeletal system. In 1985 Shirahama et al. (Biochem Biophys Res Commun 53:705-709, 1985) identified beta-2 microglobulin (MG) as the offending...

CT and MRI findings of calcified spinal meningiomas: correlation with pathological findings.

Wed, 28 Jul 2010 01:46:23 GMT

OBJECTIVE: This study was designed to present characteristic CT and MR findings of calcified spinal meningiomas that correlate with pathological findings and to assess the efficacy of CT for the detection of calcifications within a mass in comparison to MRI....

The benefits of molecular pathology in the diagnosis of musculoskeletal disease : Part I of a two-part review: soft tissue tumors.

Wed, 28 Jul 2010 01:46:19 GMT

Bone and soft tissue metabolic and neoplastic diseases are increasingly characterized by their molecular signatures. This has resulted from increased knowledge of the human genome, which has contributed to the unraveling of molecular pathways in health and...

Outcomes of airway stenting for advanced lung cancer with central airway obstruction: a single-institutional experience.

Wed, 28 Jul 2010 23:46:53 GMT

Approximately 30% of lung cancer patients will develop central airway obstruction (CAO). Interventional therapeutic bronchoscopy including airway stenting (AS) providing immediate and effective palliation is therefore essential to improve quality of life (QoL)....

Werner's syndrome as a hereditary risk factor for exocrine pancreatic cancer: Potential role of WRN in pancreatic tumorigenesis and patient-tailored therapy.

Wed, 28 Jul 2010 23:46:43 GMT

Advanced age is considered a risk factor of pancreatic cancer, but this relationship at the molecular and genetic level remains unclear. We present a clinical case series focusing on an association between pancreatic adenocarcinoma and Werner's syndrome (WS)...