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Automated Disposable Pipette Extraction

Disposable Pipette Extraction (DPX) from GERSTEL is a fast and efficient SPE technique used for a wide range of applications such as therapeutic drug monitoring. Only 200 - 250 μL of sample is needed to reach the required limits of detection using a fully automated process.

Automated Microplate Mover

The Thermo Scientific Orbitor RS was developed using technology from the Thermo Scientific RapidStak and Thermo Scientific Dimension4 product lines. It is a high-speed microplate mover offering reliable performance with flexible plate handling.

Tube Punching Functionality Added to Sample Management System

Hamilton Storage Technologies announces the addition of the SAMple Puncher, an integrated tube processing module, to its -20˚ and -80˚C Sample Access Manager (SAM) systems, enabling automated punching of tubes from their storage trays.

Accelerating Cell-Based ELISA Procedures

Agilent Automation Solutions has announced a configuration of its BioCel System that allows laboratories to fully automate cell-based ELISA procedures thereby reducing the risk of human error, contamination, and time spent on tedious manual procedures.

Automated Patch Clamp System

Fluxion Biosciences announced a product expansion for its IonFlux automated patch clamp system that includes full automation and walk-away capability.

Acoustic Dispensing

Labcyte introduced two pre-calibrated liquid class packages for use with its Echo acoustic dispensers and POD 810 plate assemblers, which move liquids with sound. This expanded capability will allow its high-throughput screening customers to not only transfer compounds in DMSO, but enables the transfer of a wide range of liquids necessary to assemble miniaturized assays for biochemical and cell-based screening.

Wellplate Transfer Robot

ASI’s Wellplate-Transfer Robot System is an automated platform designed to handle multiwell microplates. At the center of the system is the breadboard mountable WPTR‑01 three-axis robot, which automatically transfers standard wellplates from eleven-slot hotels to an ASI automated XY stage.

High-throughput Sample Processing

High-throughput Sample Processing

Thermo Fisher Scientific jointly introduced the new Capit-All IS Automated Capper/Decapper with The Automation Partnership.

Workstation for Antibody Cocktail Preparation

Workstation for Antibody Cocktail Preparation

The Beckman Coulter Antibody Cocktail Preparation workstation automatically combines antibodies and staining dyes from individual vials into tubes or vials staged on the company’s Biomek NXp deck.

Compact Liquid Handling Workstation

Compact Liquid Handling Workstation

Hamilton Robotics announces the addition of the NIMBUS iProbe to its line of compact liquid handling workstations. The new NIMBUS iProbe features up to four independent channels that can be configured with any combination of 1 ml or 5 ml pipetting heads.

Research Exchange

Publishing Data That Conform to the MIQE Guidelines

Jan 22

Minimum information for publication of Quantitative Real-Time PCR Experiments (MIQE) guidelines help researchers design qPCR experiments.

Calibration Free Analysis to Measure the Concentration of Active Proteins

Nov 23 2009

An SPR-based method, Calibration Free Concentration Analysis can be used to accurately determine the concentration of active protein in a sample, relating to the specific binding activity of the protein, and without the need for a standard.

Advances in EMCCD Technology: Making Imaging Less Arbitrary

Advances in EMCCD Technology: Making Imaging Less Arbitrary

Nov 16 2009

Recent advances in EMCCD technology have solved the problem of non-standardized measurement units by using the photoelectron to standardize imaging experiments.

10 Tips for Successful Sample Concentration and Buffer Exchange

10 Tips for Successful Sample Concentration and Buffer Exchange

Nov 6 2009

Centrifugal devices with ultrafiltration (UF) membrane can solve common problems researchers face when working with proteins.

Advantages of Monolithic Laser Combiner Technology in Confocal Microscopy Systems

Jan 6

Fluorescence microscopy techniques require a reliable light source at the desired wavelength or wavelengths, with minimal downtime for maintenance and alignment. Lasers are a popular light source, although the alignment and upkeep of laser combiners is a time-consuming prospect for many users.

Size-Exclusion Chromatography for Purification of Biomolecules

Dec 2 2009

Size-exclusion chromatography (SEC) is a popular method to separate biomolecules based on their size. Primarily, it is applied to the separation of biopolymers such as proteins and nucleic acids, i.e. water-soluble polymers.

Improving Separation During Electrophoresis

Dec 2 2009

SeparateIT gels represent a novel gel matrix for DNA electrophoresis. Gel polymers are arranged in a conceptually different way, in accordance with a new theoretical model of gel electrophoresis.

Improving Quality of ELISA

Dec 2 2009

Using ready-to-use ELISA kits from manufacturers is easy and convenient. Sometimes however, home-made ELISA is required because there is no kit available with the right antibodies or the characteristics of the available kits such as their limits of detection are not appropriate.

Using the Tecan Genesis Workstation to Automate a Cytometric Bead Array (CBA) Immunoassay

Mar 11

The poster describe the process involved in automating a Cytometric Bead Array (CBA) immunoassay developed to measure relative concentrations of serum antibodies against Tetanus (TT), Sperm Whale Myoglobin (SWM) and Keyhole Limpet Hemocyanin (KLH) in KLH-immunized volunteers.

Ensuring Quality in Assays Performed with Automated Liquid Handlers

Feb 2

The focus of this presentation is to highlight the need of ensuring quality in important assays performed with automated liquid handlers. Nearly all assays performed within a laboratory are volume-dependent. In turn, all concentrations of biological and chemical components in these assays, as well as the associated dilution protocols, are volume-dependent. Because analyte concentration is volume-dependent, an assay’s results might be falsely interpreted if liquid handler variability and inaccuracies are unknown or if the system(s) go unchecked for a long period.

Inkjet System for Protein Crystallography

Feb 1

X-ray crystallography is used routinely by scientists to obtain the three dimensional structure of a biological molecule of interest.Such information can be used to determine how a pharmaceutical interacts with a protein target and what changes might improve functionality. However, the crystallization of macromolecules still remains a serious hindrance in structural determination despite impressive advances in screening methods and technologies.

Attention Deficit & Hyperactivity in a Drosophila Memory Mutant

Attention Deficit & Hyperactivity in a Drosophila Memory Mutant

Nov 9 2009

Action selection is modulated by external stimuli either directly or via memory retrieval. In a constantly changing environment, animals have evolved attention-like processes to effectively filter the incoming sensory stream. These attention-like processes, in turn, are modulated by memory. The neurobiological nature of how attention, action selection and memory are inter-connected is unknown. We describe here new phenotypes of the memory mutant radish in the fruit fly Drosophila.

Relationship between multiple sources of perceived social support and psychological and academic adjustment in early adolescence: comparisons across gender.

Mar 8

The current study investigated gender differences in the relationship between sources of perceived support (parent, teacher, classmate, friend, school) and psychological and academic adjustment in a sample of 636 (49% male) middle school students. Longitudinal data were...

Involvement of ceramide in ischemic tolerance induced by preconditioning with sublethal oxygen-glucose deprivation in primary cultured cortical neurons of rats.

Feb 25

The complex molecular cascades of ischemic tolerance in brain cells remain unclear. Recently, sphingolipid-related metabolite ceramide has been implicated as a second messenger in many biological functions, including neuronal survival and death. The present study, therefore,...

Social intelligence and academic achievement as predictors of adolescent popularity.

Feb 24

This study compared the effects of social intelligence and cognitive intelligence, as measured by academic achievement, on adolescent popularity in two school contexts. A distinction was made between sociometric popularity, a measure of acceptance, and perceived popularity, a...

Prokariotic Cell Collection in Denmark

Nov 6 2009

I would like to know about a prokariotic cell collection in Denmark. Is there a cell bank in this country? I need a Lactobacillus strain for a fermentation assay and this information about the bank is very helpful for me.

Request for Entries

Oct 16 2009

Ask the Experts is your chance to get the answers to questions on applications, materials, methods, processes, and technologies. Email you question to bst_web@advantagemedia.com, and the editors of Bioscience Technology will find an appropriate expert to answer it. Watch this space in the future to see the questions your colleagues are posting.          

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Video:

Neuroscience Diseases of The Brain and How The Mind Emerges

Neuroscience Diseases of The Brain and How The Mind Emerges

Nov 8 2009

Dennis Choi, director of Emory Universitys Neuroscience Center, is renowned for his groundbreaking research on brain and spinal cord injury.

Podcasts:

Allen Institute for Brain Research

Allen Institute for Brain Research

Oct 14 2009

Discussed in this interview are both the mouse brain project and the human cortex project with an emphasis on the importance of these projects to neuroscience research.