Advanced CAD Offers Low-Flow Capabilities
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The Thermo Scientific Dionex Corona Veo is an advanced charged aerosol detector (CAD) for liquid chromatography (LC) engineered to increase the effectiveness of CAD technology with expanded low-flow capability and additional sensitivity compared to its previous detectors. A new FocusJet concentric nebulization system was developed specifically for the detector to enhance performance, especially for the detection of semi-volatile compounds. Compared to its past systems, the new aerosol flow path is improved for a wider range of usable LC mobile phase compositions and can accommodate a broader range of separation chemistries and column technologies. The detector is designed to make the universal detection benefits of CAD accessible with the speed and resolution of UHPLC at sub-nanogram sensitivity levels. The detector works with non-volatile and many semi-volatile compounds, from large to small molecules, including: drugs, additives, supplements, natural products, polymers and specialty chemicals. The detector can be used to evaluate relative analyte concentrations, even when standards are not available. Charged aerosol detection is considered a powerful technology that achieves near universal detection while providing consistent analyte response, regardless of an analyte’s chemical structure, for true quantitative analyses. This technique helps scientists reveal hidden contaminants earlier in development processes, saving valuable time and money.
The new detector supports HPLC and UHPLC systems from most major manufacturers. It can also complement the functions of UV detection and mass spectrometry to maximize the breadth of compound information obtained from a single analytical run.
Thermo Fisher Scientific Inc., www.thermoscientific.com/Veo