Quadrupole Mass Spectrometers

Waters introduced two new Xevo mass spectrometers and expanded the ionKey/MS System at the 62nd conference of the American Society of Mass Spectrometry (ASMS). The Waters Xevo G2-XS mass spectrometer is a new high performance benchtop quadrupole time-of-flight (QTof) mass spectrometer, while the Xevo TQ-S micro is a compact benchtop tandem quadrupole mass spectrometer.

Waters also announced the expansion of the ionKey/MS System to the SYNAPT G2-S, SYNAPT G2-Si, Xevo G2-S QTof and the newly-introduced Xevo G2-XS QTof micro mass spectrometer with new UPLC grade iKeyTM chemistries.

Additionally, Waters unveiled Progenesis QI for proteomics Version 2.0, the latest advance in proteomics data analysis software, availability of Omics LLC’s PetroOrg Petroleomics Software on the SYNAPT G2-Si for chemical composition characterization of petroleum and the exclusive rights to Prosolia's DESI (Desorption Electrospray Ionization) technology for clinical research applications for use with Waters' time-of-flight mass spectrometers.

Featuring the new XS Collision Cell, the XevoG2-XS mass spectrometer offers analytical sensitivity and selectivity in a benchtop QTof mass spectrometer. Shipment of Xevo G2-XS QTof to customer laboratories is expected to begin at the end of the second quarter with MassLynx software and in the fourth quarter under the UNIFI Scientific Information System.

The Xevo G2-XS QTof mass spectrometer combines the new XS Collision Cell with the technologies of Tof-MRM, StepWave and QuanTof to deliver optimum levels of robust sensitivity and selectivity, resulting in the detection of more low-level compounds than ever before.

For targeted quantitative experiments, Tof-MRM mode delivers a 10-fold improvement in signal-to-noise when compared to full scan mode, resulting in limits of detection and quantification that completely redefine expectations for a benchtop high resolution mass spectrometer.

The Waters Xevo TQ-S micro is designed to acquire sensitive, robust and dependable data at accelerated rates of acquisition for numerous analytes at varying concentrations. Waters intends to commence shipments of the Xevo TQ-S micro system in the third quarter.

Featuring new Xtended Dynamic Range technology, the Xevo TQ-S micro mass spectrometer offers six orders of magnitude of linear dynamic range. This is important for quantifying compounds in samples where the concentrations of individual analytes differ greatly. Furthermore, the wider the operational dynamic range, the easier it is to transfer methods between instruments of differing sensitivities.

The Xevo TQ-S micro’s new Xcelerated Ion Transfer (XIT) electronics allow the instrument to acquire as many as 500 MRMs/sec without significantly reducing peak intensities, which no other tandem quadrupole instrument currently offers.

Waters Corp., 800-252-4752, www.waters.com