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Microplate Reagents

Topics in Microplate Reagents: Analyte Quantitation | Apoptosis Detection | Plate-based Plasmid Purification Systems | Time-resolved Fluorescence Assays | Plate-based RNA Purification Systems | all topics

 

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Intracellular Delivery

The new CelLuminate VPS (Vesicle-forming Polymer System) from Biocompatibles improves the efficiency of intracellular delivery of bioactive molecules compared to conventional liposomal systems. It can deliver fluorophores to RNA, DNA, and proteins—with minimal cytotoxic effects.

Automated Multiplexed Cell-based Assays Facilitate Early Toxicology Studies

By measuring apoptosis, cell viability, and cytotoxicity in the same well, researchers are guaranteed that experimental conditions are identical for all measurements.

Apoptosis Detection Kit (10849)

The ApoStrand ELISA provides sensitive, one-step and universal detection of apoptosis in a convenient 96-well format. It detects all forms of apoptosis including events that occur without DNA breaks or without activation of specific caspases.

Homogenous Assays

HitHunter homogeneous, non-radioactive assays (Amersham Biosciences) come with clear protocols and can be read on both plate readers, and imaging platforms such as Amersham's LEADseeker Multimodality Imaging System.

TR-FRET Kinase Assays (3635)

The LanthaScreen assay platform is a time-resolved, resonance energy transfer (TR-FRET) detection technology used for high-throughput detection of kinases in drug discovery research, and measures protein-protein, protein-peptide, and DNA-protein interactions.

New Oxidizing Reagent

Resin-bound oxidizing reagent, MP-TsO-TEMPO, for alcohol oxidation, assists medicinal chemists in increasing the diversity of targeted drug compounds.

Research Exchange

Live Cell Analysis of Autophagy

Sep 4

Analysis of autophagosome formation using fluorescent cellular imaging and lentiviral biosensors.

Deconstructing 3D Cell Culture

Aug 31

3D culture models offer the potential to significantly reduce drug failure.

Safety Without Sacrifice

Safety Without Sacrifice

Jun 26

Liquid handling ergonomics and performance considerations

ELNs: The Beating Heart of a Scientist’s World

ELNs: The Beating Heart of a Scientist’s World

May 22

As ELNs deliver more benefits to researchers, the cost of changing working practice is outweighed by access to high quality, high context collaboration.

Evaluation of a New Nano-Type UV-Vis Spectrophotometer

Mar 3 2011

Analysis of one- to four-microliter size samples for nucleic acids has become routine in many life science laboratories. However, until now, available instruments require considerable manipulation of the instrument and sample; some require manually recording the data. The user must typically lower and raise the arm manually, then wipe the sample manually from the target after each analysis. And fiberoptics used in some of these instruments are subject to deterioration.

Production of Recombinant Proteins and Monoclonal Antibodies in Hollow Fiber Bioreactors

Jan 25 2011

While well-understood, robust and convenient, classical batch-style 2-D culture on non-porous supports or 3-D suspension culture in other devices are really not very biologically relevant models. Cell culture conditions can affect the quality of the antibody or protein produced.

Selecting Robots for Use in Drug Discovery and Testing

Dec 6 2010

Drug discovery and testing, with their need for speed, repeatability and verification, are ideally suited to benefit from robot automation. It is therefore not surprising that robots have been at the forefront of automation developments in both these areas.

HP Scalable Network Storage Systems for Life Sciences

Sep 13 2010

Life sciences research today is advancing exponentially, each step bringing us closer to the realization of truly personalized medicine–preventive care and treatments designed specifically for each individual. In the near future, PCPGM healthcare researchers expect to be able to use predictive genetic testing to create custom treatment plans for individuals and deliver dramatic improvements over today’s one-size-fits-all approach. But research capabilities are only part of the equation; current storage and operating capacities must also evolve to accommodate ever-expanding amounts of data before the goal of personalized medicine can be realized.

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MULTIMEDIA

Video:

Epigenetics

Aug 30

Hank & his clone Circus Hank explain the power of epigenetics, which studies the factors that determine how much or whether some genes are expressed in your body.

Podcasts:

Futures In Biotech 93: Snyder's Omics

May 17

Host: Marc Pelletier Co-Host: Andre Nantel, Ph.D. The technologies that our guest has developed are playing an important role in changing the world, not like the car, the microwave and the cell phone, but as in Drs. Flox, McCoy, and Crusher. Guest: Dr. Michael Snyder We invite...

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