BREA, Calif. (January 8, 2024) –
Beckman Coulter, Inc. today announced a collaboration with the J.
Craig Venter Institute (JCVI) on the validation of the SPRIworks
Fragment Library System I for the Illumina* Genome Analyzer. The
automated benchtop system prepares up to 10 DNA libraries in five
hours with high reproducibility and consistency.
The SPRIworks Fragment Library System I, developed by Beckman
Coulter Genomics, utilizes Solid Phase Reversible Immobilization
(SPRI) paramagnetic bead-based technology. Through elimination of
the column purification and gel electrophoresis-based
size-selection steps, the library construction workflow is amenable
to automation.
Holly Baden-Tillson, JCVI project manager said, "We’re very
excited to be first to beta test the SPRIworks Fragment Library
System I. Prior to using the platform it took a scientist a
full working day to prepare four libraries, a labor-intensive and
time-consuming process that limited throughput and turnaround time,
increased sequencing costs and decreased our scientists’
productivity. By implementing SPRIworks, we can prepare up to
20 libraries in a working day, with very consistent library
size."
Holly Baden-Tillson, JCVI scientist and project manager said, "JCVI
is very excited to be beta testing the SPRIworks Fragment Library
System I. By implementing SPRIworks, we have significantly
increased our throughput from six libraries to as many as 20
libraries in a working day, with very consistent library size and
recovery. This enhanced productivity will also help us to decrease
our library construction costs."
"The SPRIworks system was designed to simplify and automate
next-generation sequencing workflows," said Patrick J. Finn Ph.D.,
director of research and development, Beckman Coulter Genomics.
"This will enable users to prepare more samples for sequencing, and
the customer to fully utilize the growing capacity of
next-generation sequencing systems, increase operational efficiency
and maximize sequencing capability. We’re delighted to be
working with JCVI during beta testing, and the performance data
generated represents a major milestone in the development of the
SPRIworks platform. We look forward to extending this collaboration
with future SPRIworks applications."
"Simplifying a complex genomics process such as fragment library
construction for next-generation sequencing provides another
example of SPRI technology application to sequencing sample
preparation," commented Julie Moore, director of marketing for
Beckman Coulter Genomics. "Working in close collaboration with our
customers and genomic research leaders such as the JCVI allows us
to better understand the challenges faced by scientists in the
sequencing community and to develop robust solutions to their
needs."
SPRIworks Fragment Library System I will be presented at the 2010
Plant and Animal Genome, which begins January 9th in San Diego,
Calif., and is scheduled to launch in the first quarter of
2010.
About Beckman Coulter Genomics
Beckman Coulter Genomics, located in Beverly, Massachusetts, is a
leading provider of genomic services and nucleic acid purification
products, serving life-science researchers and the pharmaceutical
industry throughout the world. The company was created by combining
Beckman Coulter’s Agencourt Bioscience with the newly
acquired Cogenics. By providing technical expertise, combined with
personalized service, Beckman Coulter Genomics delivers the highest
quality data, robust analyses and innovative thinking. For more
information, visit www.beckmangenomics.com.
About Beckman Coulter
Beckman Coulter, Inc., based in Brea, California, develops,
manufactures and markets products that simplify, automate and
innovate complex biomedical tests. More than 200,000 Beckman
Coulter systems operate in laboratories around the world, supplying
critical information for improving patient health and reducing the
cost of care. Recurring revenue, consisting of supplies, test kits,
service and operating-type lease payments, represents approximately
78 percent of the company’s 2008 annual revenue of $3.1
billion. For more information, visit www.beckmancoulter.com.
Beckman Coulter and the stylized logo are registered trademarks of
Beckman Coulter, Inc.
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