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Microplate Reader Test Plates Ensure Reliable Microplate Reader Operation
Aug 20
Use of a certified test plate can help to increase efficiency when calibrating microplate readers.
Automated Imaging Assisted Cell Line Development
Aug 19
Improve titer, quality and speed in cell line development.
New Frontiers: The Changing World of Biospecimen Collection and Management
Jul 30
The growth of biomarker research and personalized medicine requires more unified and large-scale software systems to track biological materials.
Optical Imaging in Stem Cell Research
Jun 1
Developing sensitive, non-invasive technologies to monitor engraftment in vivo is essential to accelerate the clinical implementation of cell therapies.
Step up to the MIQE
Mar 30
Over the years, polymerase chain reaction (PCR) has evolved into a readily automated, high throughput quantitative technology. Real-time quantitative PCR (qPCR) has become the industry standard for the detection and quantification of nucleic acids for multiple application, including quantification of RNA levels. But a lack of consensus among researchers on how to best perform and interpret qPCR experiments presents a major hurdle for advancement of the technology. This problem is exacerbated by insufficient experimental detail in published work, which impedes the ability of others to accurately evaluate or replicate reported results.
Fast Optimization of a Multiplex Influenza Identification Panel Using a Thermal Gradient
The year 2009 was marked by the emergence of a novel influenza A (H1N1) virus that infects humans. There is a need to identify the different strains of influenza virus for purposes of monitoring the H1N1 strain pandemic and for other epidemiological and scientific purposes.
Advantages of Monolithic Laser Combiner Technology in Confocal Microscopy Systems
Jan 6
Fluorescence microscopy techniques require a reliable light source at the desired wavelength or wavelengths, with minimal downtime for maintenance and alignment. Lasers are a popular light source, although the alignment and upkeep of laser combiners is a time-consuming prospect for many users.
Size-Exclusion Chromatography for Purification of Biomolecules
Dec 2 2009
Size-exclusion chromatography (SEC) is a popular method to separate biomolecules based on their size. Primarily, it is applied to the separation of biopolymers such as proteins and nucleic acids, i.e. water-soluble polymers.
Using the Tecan Genesis Workstation to Automate a Cytometric Bead Array (CBA) Immunoassay
Mar 11
The poster describe the process involved in automating a Cytometric Bead Array (CBA) immunoassay developed to measure relative concentrations of serum antibodies against Tetanus (TT), Sperm Whale Myoglobin (SWM) and Keyhole Limpet Hemocyanin (KLH) in KLH-immunized volunteers.
Ensuring Quality in Assays Performed with Automated Liquid Handlers
Feb 2
The focus of this presentation is to highlight the need of ensuring quality in important assays performed with automated liquid handlers. Nearly all assays performed within a laboratory are volume-dependent. In turn, all concentrations of biological and chemical components in these assays, as well as the associated dilution protocols, are volume-dependent. Because analyte concentration is volume-dependent, an assay’s results might be falsely interpreted if liquid handler variability and inaccuracies are unknown or if the system(s) go unchecked for a long period.
Inkjet System for Protein Crystallography
Feb 1
X-ray crystallography is used routinely by scientists to obtain the three dimensional structure of a biological molecule of interest.Such information can be used to determine how a pharmaceutical interacts with a protein target and what changes might improve functionality. However, the crystallization of macromolecules still remains a serious hindrance in structural determination despite impressive advances in screening methods and technologies.
Attention Deficit & Hyperactivity in a Drosophila Memory Mutant
Nov 9 2009
Action selection is modulated by external stimuli either directly or via memory retrieval. In a constantly changing environment, animals have evolved attention-like processes to effectively filter the incoming sensory stream. These attention-like processes, in turn, are modulated by memory. The neurobiological nature of how attention, action selection and memory are inter-connected is unknown. We describe here new phenotypes of the memory mutant radish in the fruit fly Drosophila.
Structural basis for the camp-dependent gating in human HCN4 channel.
37 minutes ago
Hyperpolarization-activated cAMP-regulated (HCN) channels play important physiological roles in both cardiovascular and central nervous systems. Among the four HCN isoforms, HCN2 and HCN4 show high expression levels in the human heart, with HCN4 being the major...
[Effects of bioactive molecules of Beta vulgaris L. ssp. esculenta var. rubra on metastatic prostate cancer.]
8 hours ago
Several reports are known about the effects of nutrition supplements in the improvement of quality of life of patients with tumor, however, the physiological background remains largely unknown. Table beet affects numerous biochemical reactions, enzymes and...
A quantitative study of brainstem projections from lamina I neurons in the cervical and lumbar enlargement of the rat.
9 hours ago
Lamina I of the rat spinal cord contains neurons that project to various brain areas including thalamus, periaqueductal grey matter (PAG), lateral parabrachial area (LPb), caudal ventrolateral medulla and a region in dorsal medulla that includes the nucleus...
Biomimetic coatings for bone tissue engineering of critical-sized defects.
14 hours ago
The repair of critical-sized bone defects is still challenging in the fields of implantology, maxillofacial surgery and orthopaedics. Current therapies such as autografts and allografts are associated with various limitations. Cytokine-based bone tissue engineering has been...
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Prokariotic Cell Collection in Denmark
Nov 6 2009
I would like to know about a prokariotic cell collection in Denmark. Is there a cell bank in this country? I need a Lactobacillus strain for a fermentation assay and this information about the bank is very helpful for me.
Request for Entries
Oct 16 2009
Ask the Experts is your chance to get the answers to questions on applications, materials, methods, processes, and technologies. Email you question to bst_web@advantagemedia.com, and the editors of Bioscience Technology will find an appropriate expert to answer it. Watch this space in the future to see the questions your colleagues are posting.
Gene discovery could yield treatments for nearsightedness
3 hours ago
MIT researchers develop a way to funnel solar energy
4 hours ago
Engineers make artificial skin out of nanowires
Scripps Research scientists solve long-standing mystery of protein 'quality control' mechanism
Scientists find drugs that may fight bat disease
Henry Ford Hospital study: hVISA linked to high mortality
6 hours ago
Statement from GE Healthcare on Settlement with Professor Henrik Thomsen
Sep 11
Sep 11 | News
Updated Phase 2 Data With Flutemetamol Published in Annals of Neurology
Sep 9 | News
Scott Garrett Resigns as Chairman, President and CEO of Beckman Coulter
Sep 8 | News
Gilson announces the launch of PIPETMAN.EU
Aug 20 | News
Beckman Coulter Launches New Data Manager REMISOL Advance v1.4
Aug 16 | News
Beckman Coulter Signs Record Deal to Provide Integrated Testing Solutions to CML Healthcare, a Leading Laboratory Services Provider in Ontario, Canada
Aug 5 | News
Aug 16
Sep 8
Aug 5
Beckman Coulter Exhibits More Solutions for Attendees of 2010 AACC/ASCLS Annual Meeting and Clinical Lab Expo
Jul 26
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Viewing SureFocus Slides
Jun 11
A demonstration of SureFocus Microscope Slides in the review of AFB Smears. SureFocus Slides are a patent-pending breakthrough in tuberculosis detection, as their fluorescent staining circle remains visible during review, Fluorescence Microscopy.
Allen Institute for Brain Research
Oct 14 2009
Discussed in this interview are both the mouse brain project and the human cortex project with an emphasis on the importance of these projects to neuroscience research.