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How to Build an Integrated Microscopy System for Live Cell Mechanotransduction Studies
Aug 2
A new integrated microscopy system allows scientists to simultaneously stimulate and image live cell response in real-time.
Tips for Reducing Static Electricity
Aug 1
Static electricity can affect automated instrumentation within the lab.
Microscopes for the Non-Microscopist: Multidisciplinary Research Using Optical Imaging
Jul 5
High quality microscopy is increasingly used by scientists in new areas of research.
Bringing the Cell Image into Focus
Nov 2 2010
Improvements in transmission electron microscope (TEM) technology increase the power of this imaging tool for the study of cell biology.
Evaluation of a New Nano-Type UV-Vis Spectrophotometer
Mar 3
Analysis of one- to four-microliter size samples for nucleic acids has become routine in many life science laboratories. However, until now, available instruments require considerable manipulation of the instrument and sample; some require manually recording the data. The user must typically lower and raise the arm manually, then wipe the sample manually from the target after each analysis. And fiberoptics used in some of these instruments are subject to deterioration.
Production of Recombinant Proteins and Monoclonal Antibodies in Hollow Fiber Bioreactors
Jan 25
While well-understood, robust and convenient, classical batch-style 2-D culture on non-porous supports or 3-D suspension culture in other devices are really not very biologically relevant models. Cell culture conditions can affect the quality of the antibody or protein produced.
Selecting Robots for Use in Drug Discovery and Testing
Dec 6 2010
Drug discovery and testing, with their need for speed, repeatability and verification, are ideally suited to benefit from robot automation. It is therefore not surprising that robots have been at the forefront of automation developments in both these areas.
HP Scalable Network Storage Systems for Life Sciences
Sep 13 2010
Life sciences research today is advancing exponentially, each step bringing us closer to the realization of truly personalized medicine–preventive care and treatments designed specifically for each individual. In the near future, PCPGM healthcare researchers expect to be able to use predictive genetic testing to create custom treatment plans for individuals and deliver dramatic improvements over today’s one-size-fits-all approach. But research capabilities are only part of the equation; current storage and operating capacities must also evolve to accommodate ever-expanding amounts of data before the goal of personalized medicine can be realized.
Using the Tecan Genesis Workstation to Automate a Cytometric Bead Array (CBA) Immunoassay
Mar 11 2010
The poster describe the process involved in automating a Cytometric Bead Array (CBA) immunoassay developed to measure relative concentrations of serum antibodies against Tetanus (TT), Sperm Whale Myoglobin (SWM) and Keyhole Limpet Hemocyanin (KLH) in KLH-immunized volunteers.
Ensuring Quality in Assays Performed with Automated Liquid Handlers
Feb 2 2010
The focus of this presentation is to highlight the need of ensuring quality in important assays performed with automated liquid handlers. Nearly all assays performed within a laboratory are volume-dependent. In turn, all concentrations of biological and chemical components in these assays, as well as the associated dilution protocols, are volume-dependent. Because analyte concentration is volume-dependent, an assay’s results might be falsely interpreted if liquid handler variability and inaccuracies are unknown or if the system(s) go unchecked for a long period.
Inkjet System for Protein Crystallography
Feb 1 2010
X-ray crystallography is used routinely by scientists to obtain the three dimensional structure of a biological molecule of interest.Such information can be used to determine how a pharmaceutical interacts with a protein target and what changes might improve functionality. However, the crystallization of macromolecules still remains a serious hindrance in structural determination despite impressive advances in screening methods and technologies.
Attention Deficit & Hyperactivity in a Drosophila Memory Mutant
Nov 9 2009
Action selection is modulated by external stimuli either directly or via memory retrieval. In a constantly changing environment, animals have evolved attention-like processes to effectively filter the incoming sensory stream. These attention-like processes, in turn, are modulated by memory. The neurobiological nature of how attention, action selection and memory are inter-connected is unknown. We describe here new phenotypes of the memory mutant radish in the fruit fly Drosophila.
Using Java for distributed computing in the Gaia satellite data processing
5 hours ago
In recent years Java has matured to a stable easy-to-use language with the flexibility of an interpreter (for reflection etc.) but the performance and type checking of a compiled language. When we started using Java for astronomical applications around 1999 they were the first...
Schrödinger–Newton ‘collapse’ of the wavefunction
It has been suggested that the nonlinear Schr\"odinger-Newton equation might approximate the coupling of quantum mechanics with gravitation, particularly in the context of the M{\o}ller-Rosenfeld semiclassical theory. Numerical results for the spherically symmetric,...
Morphology, dynamics and plasma parameters of plumes and inter-plume regions in solar coronal holes
Coronal plumes, which extend from solar coronal holes (CH) into the high corona and - possibly - into the solar wind (SW), can now continuously be studied with modern telescopes and spectrometers on spacecraft, in addition to investigations from the ground, in particular,...
Enteral omega-3 fatty acid, gamma-linolenic acid, and antioxidant supplementation in acute lung injury.
8 hours ago
The omega-3 (n-3) fatty acids docosahexaenoic acid and eicosapentaenoic acid, along with γ-linolenic acid and antioxidants, may modulate systemic inflammatory response and improve oxygenation and outcomes in patients with acute lung injury. To...
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Prokariotic Cell Collection in Denmark
Nov 6 2009
I would like to know about a prokariotic cell collection in Denmark. Is there a cell bank in this country? I need a Lactobacillus strain for a fermentation assay and this information about the bank is very helpful for me.
Request for Entries
Oct 16 2009
Ask the Experts is your chance to get the answers to questions on applications, materials, methods, processes, and technologies. Email you question to bst_web@advantagemedia.com, and the editors of Bioscience Technology will find an appropriate expert to answer it. Watch this space in the future to see the questions your colleagues are posting.
Abbott Labs plans to split into 2 companies
39 minutes ago
Jazz Pharmaceuticals shares fall after FDA warning
10 hours ago
Study: High blood pressure ups birth defect risk
14 hours ago
Summary Box: J&J 3Q profit falls, sales rise a bit
16 hours ago
Heart failure hospital stays fall, saving billions
Fitch sets investor grade on PerkinElmer debt
Study: Vaccine reduces malaria in African children
Agilent Technologies Awards 2011 Russell Varian Prize for Innovation in Nuclear Magnetic Resonance
Sep 29 | News
JEOL USA Partners with Chilean Agent Arquimed
Sep 27 | News
Bruker Announces Agreement to Acquire CETR
Sep 13 | News
FEI, OHSU Partner to Create a 'Living Lab for Cell Biology'
Millipore Acquires Remaining Ownership of its Joint Venture in India to Accelerate Growth in the Region
Sep 2 | News
DNA2.0 Obtains Key Protein Engineering Patent
Aug 24 | News
Reinnervate Expands Distribution Network for Alvetex in Asia and Australia
Complete List of Substantially Equivalent 510(k) Device Applications
Oct 15
Comunicado de la FDA sobre la seguridad de los medicamentos: Informes sobre un efecto adverso raro pero grave y potencialmente fatal del uso de benzocaína en gel o l...
Oct 13
Preventing Surgical Fires
FDA Drug Safety Communication: Sprycel (dasatinib) and risk of pulmonary arterial hypertension
Oct 11
CooperVision Avaira Toric Soft Contact Lenses: Class 1 Recall- Unintended Residue on Lenses
Oct 14
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Viewing SureFocus Slides
Jun 11 2010
A demonstration of SureFocus Microscope Slides in the review of AFB Smears. SureFocus Slides are a patent-pending breakthrough in tuberculosis detection, as their fluorescent staining circle remains visible during review, Fluorescence Microscopy.
Allen Institute for Brain Research
Oct 14 2009
Discussed in this interview are both the mouse brain project and the human cortex project with an emphasis on the importance of these projects to neuroscience research.