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Three Tips to Help Manage Customization in Genomics LIMS Implementations
Nov 21
Labs must consider three elements in evaluating genomics laboratory information management system (LIMS) to support the ever-changing workflow characteristics of next-generation sequencing.
How to Build an Integrated Microscopy System for Live Cell Mechanotransduction Studies
Aug 2
A new integrated microscopy system allows scientists to simultaneously stimulate and image live cell response in real-time.
Tips for Reducing Static Electricity
Aug 1
Static electricity can affect automated instrumentation within the lab.
Microscopes for the Non-Microscopist: Multidisciplinary Research Using Optical Imaging
Jul 5
High quality microscopy is increasingly used by scientists in new areas of research.
Evaluation of a New Nano-Type UV-Vis Spectrophotometer
Mar 3
Analysis of one- to four-microliter size samples for nucleic acids has become routine in many life science laboratories. However, until now, available instruments require considerable manipulation of the instrument and sample; some require manually recording the data. The user must typically lower and raise the arm manually, then wipe the sample manually from the target after each analysis. And fiberoptics used in some of these instruments are subject to deterioration.
Production of Recombinant Proteins and Monoclonal Antibodies in Hollow Fiber Bioreactors
Jan 25
While well-understood, robust and convenient, classical batch-style 2-D culture on non-porous supports or 3-D suspension culture in other devices are really not very biologically relevant models. Cell culture conditions can affect the quality of the antibody or protein produced.
Selecting Robots for Use in Drug Discovery and Testing
Dec 6 2010
Drug discovery and testing, with their need for speed, repeatability and verification, are ideally suited to benefit from robot automation. It is therefore not surprising that robots have been at the forefront of automation developments in both these areas.
HP Scalable Network Storage Systems for Life Sciences
Sep 13 2010
Life sciences research today is advancing exponentially, each step bringing us closer to the realization of truly personalized medicine–preventive care and treatments designed specifically for each individual. In the near future, PCPGM healthcare researchers expect to be able to use predictive genetic testing to create custom treatment plans for individuals and deliver dramatic improvements over today’s one-size-fits-all approach. But research capabilities are only part of the equation; current storage and operating capacities must also evolve to accommodate ever-expanding amounts of data before the goal of personalized medicine can be realized.
Using the Tecan Genesis Workstation to Automate a Cytometric Bead Array (CBA) Immunoassay
Mar 11 2010
The poster describe the process involved in automating a Cytometric Bead Array (CBA) immunoassay developed to measure relative concentrations of serum antibodies against Tetanus (TT), Sperm Whale Myoglobin (SWM) and Keyhole Limpet Hemocyanin (KLH) in KLH-immunized volunteers.
Ensuring Quality in Assays Performed with Automated Liquid Handlers
Feb 2 2010
The focus of this presentation is to highlight the need of ensuring quality in important assays performed with automated liquid handlers. Nearly all assays performed within a laboratory are volume-dependent. In turn, all concentrations of biological and chemical components in these assays, as well as the associated dilution protocols, are volume-dependent. Because analyte concentration is volume-dependent, an assay’s results might be falsely interpreted if liquid handler variability and inaccuracies are unknown or if the system(s) go unchecked for a long period.
Inkjet System for Protein Crystallography
Feb 1 2010
X-ray crystallography is used routinely by scientists to obtain the three dimensional structure of a biological molecule of interest.Such information can be used to determine how a pharmaceutical interacts with a protein target and what changes might improve functionality. However, the crystallization of macromolecules still remains a serious hindrance in structural determination despite impressive advances in screening methods and technologies.
Attention Deficit & Hyperactivity in a Drosophila Memory Mutant
Nov 9 2009
Action selection is modulated by external stimuli either directly or via memory retrieval. In a constantly changing environment, animals have evolved attention-like processes to effectively filter the incoming sensory stream. These attention-like processes, in turn, are modulated by memory. The neurobiological nature of how attention, action selection and memory are inter-connected is unknown. We describe here new phenotypes of the memory mutant radish in the fruit fly Drosophila.
Counting solutions from finite samplings
11 hours ago
We formulate the solution counting problem within the framework of inverse Ising problem and use belief propagation equations to estimate the entropy whose value provides an upper bound on the true one. We test this idea on both diluted models (random 2-SAT and 3-SAT problems)...
Study of the Higgs-Yukawa theory in the strong-Yukawa coupling regime
In this article, we present an ongoing lattice study of the Higgs-Yukawa model, in the regime of strong-Yukawa coupling, using overlap fermions. We investigated the phase structure in this regime by computing the Higgs vacuum expectation value, and by exploring the finite-size...
The Forward-Backward Top Asymmetry in a Singlet extension of the MSSM
The CDF and D0 collaborations have recently reported a large forward-backward asymmetry in the ttbar system which deviates from the next to-leading order QCD standard model prediction. We study the asymmetry in the ttbar system within the framework of singlet extensions of the...
Molecular characterization and taxonomy of grapevine leafroll-associated virus 7
The complete nucleotide sequence of an Albanian isolate of grapevine leafroll-associated virus 7 (GLRaV-7-Alb) was determined. The viral genome consists of 16,404 nucleotides and has nine open reading frames (ORFs) that potentially encode proteins, most of which...
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Prokariotic Cell Collection in Denmark
Nov 6 2009
I would like to know about a prokariotic cell collection in Denmark. Is there a cell bank in this country? I need a Lactobacillus strain for a fermentation assay and this information about the bank is very helpful for me.
Request for Entries
Oct 16 2009
Ask the Experts is your chance to get the answers to questions on applications, materials, methods, processes, and technologies. Email you question to bst_web@advantagemedia.com, and the editors of Bioscience Technology will find an appropriate expert to answer it. Watch this space in the future to see the questions your colleagues are posting.
University gives students space to work 'remotely'
4 hours ago
University wins Times Higher Award
17 hours ago
Fellowship for Professor Ian Robertson
Farmers' market
Pharmacy education centre awarded new NHS contract
Open meetings - what did you think?
19 hours ago
Increased safety measures
20 hours ago
Research on Dendrites Wins 2011 Eppendorf and Science Prize
Nov 13 | News
Sartorius Concludes Agreement to Acquire the Liquid Handling Business of Biohit
Oct 27 | News
Agilent Technologies Awards 2011 Russell Varian Prize for Innovation in Nuclear Magnetic Resonance
Sep 29 | News
JEOL USA Partners with Chilean Agent Arquimed
Sep 27 | News
Bruker Announces Agreement to Acquire CETR
Sep 13 | News
FEI, OHSU Partner to Create a 'Living Lab for Cell Biology'
Millipore Acquires Remaining Ownership of its Joint Venture in India to Accelerate Growth in the Region
Sep 2 | News
Medical engineering pioneers’ Royal prize
Nov 24
USS Members’ Annual Report 2010/11 published
Postgraduate Open Day
University wins Queen's Anniversary Prize for its Nuclear work
17 hours ago | News
19 hours ago | News
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Viewing SureFocus Slides
Jun 11 2010
A demonstration of SureFocus Microscope Slides in the review of AFB Smears. SureFocus Slides are a patent-pending breakthrough in tuberculosis detection, as their fluorescent staining circle remains visible during review, Fluorescence Microscopy.
Allen Institute for Brain Research
Oct 14 2009
Discussed in this interview are both the mouse brain project and the human cortex project with an emphasis on the importance of these projects to neuroscience research.