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Genetic Causes Identified for Disturbances in Lipid Metabolism

Neuherberg, December 27, 2009. Scientists of Helmholtz Zentrum München led by Professor Karsten...

Dickensian Christmas dreamt up by marketers, says historian

The idealised picture of a Dickensian Christmas, where contented families innocently played parlour games by a twinkling Christmas tree is a misleading invention of marketers, according to new research.

Jodrell Bank dragon hunt will be Christmas cracker

It’s proved Einstein’s theory of relativity, tracked the launch of Sputnik and probed the origins of the Universe – now the iconic Lovell Telescope at Jodrell Bank is being used to find dragons.

Enterprise Scholars step up to boot camp

The University of Leeds Enterprise Scholars gathered at a special 'boot camp' at Weetwood Hall earlier this week aimed at boosting their chances of business success.

GDP is misleading measure of wealth, says top economist

The most commonly used measure of overall economic output is misleading and inaccurate, according to one of the world’s leading economists.

'Particle soup' discovery will improve climate predictions

New research from scientists at The University of Manchester is set to improve predictions about climate and air quality – and make life easier for those suffering from respiratory problems.

Rock defeats Phelps in butterfly

A University of Manchester law student has produced the race of a lifetime to defeat the world’s greatest ever swimmer - by a body length.

Rock music from the Cumbrian hills

The world-famous percussionist Dame Evelyn Glennie is taking part in a new project which introduces children to geology by constructing and playing 'musical rocks'.

Sticks and bones: Tree study to help orthopaedic surgeons

A study on why tree branches buckle or split, rather than break cleanly, could help orthopaedic surgeons do a better repair job on children’s broken bones.

Maths-based solution will boost mining profits

A team from the School of Mathematics and Manchester Business School has developed a novel means of helping mining companies accurately calculate the value of their reserves.

Research Exchange

Calibration Free Analysis to Measure the Concentration of Active Proteins

Nov 23

An SPR-based method, Calibration Free Concentration Analysis can be used to accurately determine the concentration of active protein in a sample, relating to the specific binding activity of the protein, and without the need for a standard.

Advances in EMCCD Technology: Making Imaging Less Arbitrary

Nov 16

Recent advances in EMCCD technology have solved the problem of non-standardized measurement units by using the photoelectron to standardize imaging experiments.

10 Tips for Successful Sample Concentration and Buffer Exchange

Nov 6

Centrifugal devices with ultrafiltration (UF) membrane can solve common problems researchers face when working with proteins.

Meeting the Challenges of Long-term Time-lapse Imaging

Oct 26

Recent technological developments in the sequence capture of cellular events through a light microscope can be combined to image multiple independent experiments automatically, with many advantages.

Size-Exclusion Chromatography for Purification of Biomolecules

Dec 2

Size-exclusion chromatography (SEC) is a popular method to separate biomolecules based on their size. Primarily, it is applied to the separation of biopolymers such as proteins and nucleic acids, i.e. water-soluble polymers.

Improving Separation During Electrophoresis

Dec 2

SeparateIT gels represent a novel gel matrix for DNA electrophoresis. Gel polymers are arranged in a conceptually different way, in accordance with a new theoretical model of gel electrophoresis.

Improving Quality of ELISA

Dec 2

Using ready-to-use ELISA kits from manufacturers is easy and convenient. Sometimes however, home-made ELISA is required because there is no kit available with the right antibodies or the characteristics of the available kits such as their limits of detection are not appropriate.

Nucleic Acid Decontamination with the ExitusPlus Technology

Dec 2

Using new methods that detect extremely low levels of DNA molecules, researchers investigated the molecular mechanism of action of various commercially available DNA decontamination reagents. They found that when using high concentrations of DNA and short incubation times, none of the conventional reagents destroyed DNA molecules efficiently, despite their corrosive or even toxic properties.

Attention Deficit & Hyperactivity in a Drosophila Memory Mutant

Attention Deficit & Hyperactivity in a Drosophila Memory Mutant

Nov 9

Action selection is modulated by external stimuli either directly or via memory retrieval. In a constantly changing environment, animals have evolved attention-like processes to effectively filter the incoming sensory stream. These attention-like processes, in turn, are modulated by memory. The neurobiological nature of how attention, action selection and memory are inter-connected is unknown. We describe here new phenotypes of the memory mutant radish in the fruit fly Drosophila.

Mechanisms of plasticity in simple taxis behaviors in Drosophila

Nov 8

Like the proverbial moth drawn to the candle flame, the fruit fly Drosophila also stereotypically approaches light sources. This positive phototaxis is the archetypal example of hard-wired input-output behaviors.

Live cell imaging of mutant and wild-type GABA-A receptor trafficking using a novel reporter protein

Nov 8

Efficient signaling in the brain requires precise regulation and targeting of cell surface ion-channels. Mutations in these channels associated with inherited diseases can cause improper targeting and reduced surface expression.

ADP-Glo™: An Ideal Approach to Monitor the Activity of Protein Kinases and Beyond

Oct 16

Because of its versatility (alltypesofsubstrates), robustness (Z’>0.8), rapidperformance, and its ease of use, the luminescence based Kinase Glo® assay platform has gained wide acceptance in many drug screening programs for protein kinase inhibitors.

The maize root stem cell niche: a partnership between two sister cell populations.

4 hours ago

Using transcript profile analysis, we explored the nature of the stem cell niche in roots of maize (Zea mays). Toward assessing a role for specific genes in the establishment and maintenance of the niche, we perturbed the niche and simultaneously monitored the...

Household Transmission of 2009 Pandemic Influenza A (H1N1) Virus in the United States

19 hours ago

Background As of June 11, 2009, a total of 17,855 probable or confirmed cases of 2009 pandemic influenza A (H1N1) had been reported in the United States. Risk factors for transmission remain largely uncharacterized. We characterize the risk factors and describe the transmission...

Prokariotic Cell Collection in Denmark

Nov 6

I would like to know about a prokariotic cell collection in Denmark. Is there a cell bank in this country? I need a Lactobacillus strain for a fermentation assay and this information about the bank is very helpful for me.

Request for Entries

Oct 16

Ask the Experts is your chance to get the answers to questions on applications, materials, methods, processes, and technologies. Email you question to bst_web@advantagemedia.com, and the editors of Bioscience Technology will find an appropriate expert to answer it. Watch this space in the future to see the questions your colleagues are posting.

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Video:

Neuroscience Diseases of The Brain and How The Mind Emerges

Neuroscience Diseases of The Brain and How The Mind Emerges

Nov 8

Dennis Choi, director of Emory Universitys Neuroscience Center, is renowned for his groundbreaking research on brain and spinal cord injury.

Podcasts:

Allen Institute for Brain Research

Allen Institute for Brain Research

Oct 14

Discussed in this interview are both the mouse brain project and the human cortex project with an emphasis on the importance of these projects to neuroscience research.