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New Frontiers: The Changing World of Biospecimen Collection and Management
Jul 30
The growth of biomarker research and personalized medicine requires more unified and large-scale software systems to track biological materials.
Optical Imaging in Stem Cell Research
Jun 1
Developing sensitive, non-invasive technologies to monitor engraftment in vivo is essential to accelerate the clinical implementation of cell therapies.
Standing Up in a Court of Law
Private forensic testing laboratory ensures data integrity with advanced calibration systems.
Simultaneous Measurement of Multiple Signaling Pathways in Human Leukemias Using Flow Cytometry
May 24
Next generation assays will need to be robust and standardized in order to make the transition from a research procedure to a routine clinical assay. Flow cytometry provides a unique and sensitive method to accomplish these requirements.
Step up to the MIQE
Mar 30
Over the years, polymerase chain reaction (PCR) has evolved into a readily automated, high throughput quantitative technology. Real-time quantitative PCR (qPCR) has become the industry standard for the detection and quantification of nucleic acids for multiple application, including quantification of RNA levels. But a lack of consensus among researchers on how to best perform and interpret qPCR experiments presents a major hurdle for advancement of the technology. This problem is exacerbated by insufficient experimental detail in published work, which impedes the ability of others to accurately evaluate or replicate reported results.
Fast Optimization of a Multiplex Influenza Identification Panel Using a Thermal Gradient
The year 2009 was marked by the emergence of a novel influenza A (H1N1) virus that infects humans. There is a need to identify the different strains of influenza virus for purposes of monitoring the H1N1 strain pandemic and for other epidemiological and scientific purposes.
Advantages of Monolithic Laser Combiner Technology in Confocal Microscopy Systems
Jan 6
Fluorescence microscopy techniques require a reliable light source at the desired wavelength or wavelengths, with minimal downtime for maintenance and alignment. Lasers are a popular light source, although the alignment and upkeep of laser combiners is a time-consuming prospect for many users.
Size-Exclusion Chromatography for Purification of Biomolecules
Dec 2 2009
Size-exclusion chromatography (SEC) is a popular method to separate biomolecules based on their size. Primarily, it is applied to the separation of biopolymers such as proteins and nucleic acids, i.e. water-soluble polymers.
Using the Tecan Genesis Workstation to Automate a Cytometric Bead Array (CBA) Immunoassay
Mar 11
The poster describe the process involved in automating a Cytometric Bead Array (CBA) immunoassay developed to measure relative concentrations of serum antibodies against Tetanus (TT), Sperm Whale Myoglobin (SWM) and Keyhole Limpet Hemocyanin (KLH) in KLH-immunized volunteers.
Ensuring Quality in Assays Performed with Automated Liquid Handlers
Feb 2
The focus of this presentation is to highlight the need of ensuring quality in important assays performed with automated liquid handlers. Nearly all assays performed within a laboratory are volume-dependent. In turn, all concentrations of biological and chemical components in these assays, as well as the associated dilution protocols, are volume-dependent. Because analyte concentration is volume-dependent, an assay’s results might be falsely interpreted if liquid handler variability and inaccuracies are unknown or if the system(s) go unchecked for a long period.
Inkjet System for Protein Crystallography
Feb 1
X-ray crystallography is used routinely by scientists to obtain the three dimensional structure of a biological molecule of interest.Such information can be used to determine how a pharmaceutical interacts with a protein target and what changes might improve functionality. However, the crystallization of macromolecules still remains a serious hindrance in structural determination despite impressive advances in screening methods and technologies.
Attention Deficit & Hyperactivity in a Drosophila Memory Mutant
Nov 9 2009
Action selection is modulated by external stimuli either directly or via memory retrieval. In a constantly changing environment, animals have evolved attention-like processes to effectively filter the incoming sensory stream. These attention-like processes, in turn, are modulated by memory. The neurobiological nature of how attention, action selection and memory are inter-connected is unknown. We describe here new phenotypes of the memory mutant radish in the fruit fly Drosophila.
Mountain mining damages streams
9 hours ago
Study shows that stripping mountains for coal has a much greater impact than urban growth. West Virginia’s mountains contain valuable low-sulphur coal.P. Souza/Chicago Tribune/MCT/Newscom The controversial practice of stripping off the tops of mountains to mine coal, long...
Oceanography: Dead in the water
Every summer for the past nine years, water with lethally low concentrations of oxygen has appeared off the Oregon coast. The hypoxia may be a sign of things to come elsewhere, finds Virginia Gewin. Download a PDF of this story. The dead fish were one of the first signs. In...
The Eat Smart Study: A randomised controlled trial of a reduced carbohydrate versus a low fat diet for weight loss in obese adolescents.
ABSTRACT: BACKGROUND: Despite the recognition of obesity in young people as a key health issue, there is limited evidence to inform health professionals regarding the most appropriate treatment options. The Eat Smart study aims to contribute to the knowledge...
France digs deep for nuclear waste
Geological storage of long-lived radioactive material is moving closer to reality in Europe, says Declan Butler. The tunnels of the Bure laboratory are still being carved out of the 150 million-year-old rock.B. Tinoco/ANDRA "It'll be about 8 minutes before we reach the...
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Prokariotic Cell Collection in Denmark
Nov 6 2009
I would like to know about a prokariotic cell collection in Denmark. Is there a cell bank in this country? I need a Lactobacillus strain for a fermentation assay and this information about the bank is very helpful for me.
Request for Entries
Oct 16 2009
Ask the Experts is your chance to get the answers to questions on applications, materials, methods, processes, and technologies. Email you question to bst_web@advantagemedia.com, and the editors of Bioscience Technology will find an appropriate expert to answer it. Watch this space in the future to see the questions your colleagues are posting.
FDA panel vouches for epilepsy drug effectiveness
4 hours ago
Endologix denies infringing on Bard patent
5 hours ago
University of Maryland co-sponsors International Conference on the Effects of Noise on Aquatic Life
6 hours ago
Good news: Light and moderate physical activity reduces the risk of early death
7 hours ago
New diabetes risk assessment developed
Novacare LLC Products: Recall - Undeclared Drug Ingredient
J&J discloses more subpoenas over consumer recalls
Beckman Coulter Signs Record Deal to Provide Integrated Testing Solutions to CML Healthcare, a Leading Laboratory Services Provider in Ontario, Canada
Aug 5 | News
Beckman Coulter Exhibits More Solutions for Attendees of 2010 AACC/ASCLS Annual Meeting and Clinical Lab Expo
Jul 26 | News
Merck KGaA Completes Millipore Acquisition and Launches New EMD Millipore Division
Jul 23 | News
Thermo Fisher Scientific and Intrinsic Bioprobes Announce Alliance in Mass Spectrometric Immunoassay (MSIA) Workflow Development
Jul 21 | News
ACE replacing Millipore in S&P 500
Jul 8 | News
Компания GE Healthcare провела обучающий семинар по современным методам диагностики рака молочной железы для медицинских специалистов из российских регионов
Jul 6 | News
Beckman Coulter Genomics and DNA Genotek Enhance DNA Isolation and Purification
Single cell injections
Aug 9
Nerve Connections Regenerated After Spinal Cord Injury
Aug 8
Genetic differences that make some people susceptible to meningitis revealed in major new study
Deep Brain Stimulation shows promise for patients with Alzheimer's
Aug 4
7 hours ago | News
Menstrual cramps may alter brain structure
23 hours ago | News
Spinal muscular atrophy may also affect the heart
Pumps and Tubing Catalog
Aug 10 | Products
Compact Vacuum Pumps for Filtration and SPE
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Viewing SureFocus Slides
Jun 11
A demonstration of SureFocus Microscope Slides in the review of AFB Smears. SureFocus Slides are a patent-pending breakthrough in tuberculosis detection, as their fluorescent staining circle remains visible during review, Fluorescence Microscopy.
Allen Institute for Brain Research
Oct 14 2009
Discussed in this interview are both the mouse brain project and the human cortex project with an emphasis on the importance of these projects to neuroscience research.