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Microplate Reader Test Plates Ensure Reliable Microplate Reader Operation
Aug 20
Use of a certified test plate can help to increase efficiency when calibrating microplate readers.
Automated Imaging Assisted Cell Line Development
Aug 19
Improve titer, quality and speed in cell line development.
New Frontiers: The Changing World of Biospecimen Collection and Management
Jul 30
The growth of biomarker research and personalized medicine requires more unified and large-scale software systems to track biological materials.
Optical Imaging in Stem Cell Research
Jun 1
Developing sensitive, non-invasive technologies to monitor engraftment in vivo is essential to accelerate the clinical implementation of cell therapies.
Step up to the MIQE
Mar 30
Over the years, polymerase chain reaction (PCR) has evolved into a readily automated, high throughput quantitative technology. Real-time quantitative PCR (qPCR) has become the industry standard for the detection and quantification of nucleic acids for multiple application, including quantification of RNA levels. But a lack of consensus among researchers on how to best perform and interpret qPCR experiments presents a major hurdle for advancement of the technology. This problem is exacerbated by insufficient experimental detail in published work, which impedes the ability of others to accurately evaluate or replicate reported results.
Fast Optimization of a Multiplex Influenza Identification Panel Using a Thermal Gradient
The year 2009 was marked by the emergence of a novel influenza A (H1N1) virus that infects humans. There is a need to identify the different strains of influenza virus for purposes of monitoring the H1N1 strain pandemic and for other epidemiological and scientific purposes.
Advantages of Monolithic Laser Combiner Technology in Confocal Microscopy Systems
Jan 6
Fluorescence microscopy techniques require a reliable light source at the desired wavelength or wavelengths, with minimal downtime for maintenance and alignment. Lasers are a popular light source, although the alignment and upkeep of laser combiners is a time-consuming prospect for many users.
Size-Exclusion Chromatography for Purification of Biomolecules
Dec 2 2009
Size-exclusion chromatography (SEC) is a popular method to separate biomolecules based on their size. Primarily, it is applied to the separation of biopolymers such as proteins and nucleic acids, i.e. water-soluble polymers.
Using the Tecan Genesis Workstation to Automate a Cytometric Bead Array (CBA) Immunoassay
Mar 11
The poster describe the process involved in automating a Cytometric Bead Array (CBA) immunoassay developed to measure relative concentrations of serum antibodies against Tetanus (TT), Sperm Whale Myoglobin (SWM) and Keyhole Limpet Hemocyanin (KLH) in KLH-immunized volunteers.
Ensuring Quality in Assays Performed with Automated Liquid Handlers
Feb 2
The focus of this presentation is to highlight the need of ensuring quality in important assays performed with automated liquid handlers. Nearly all assays performed within a laboratory are volume-dependent. In turn, all concentrations of biological and chemical components in these assays, as well as the associated dilution protocols, are volume-dependent. Because analyte concentration is volume-dependent, an assay’s results might be falsely interpreted if liquid handler variability and inaccuracies are unknown or if the system(s) go unchecked for a long period.
Inkjet System for Protein Crystallography
Feb 1
X-ray crystallography is used routinely by scientists to obtain the three dimensional structure of a biological molecule of interest.Such information can be used to determine how a pharmaceutical interacts with a protein target and what changes might improve functionality. However, the crystallization of macromolecules still remains a serious hindrance in structural determination despite impressive advances in screening methods and technologies.
Attention Deficit & Hyperactivity in a Drosophila Memory Mutant
Nov 9 2009
Action selection is modulated by external stimuli either directly or via memory retrieval. In a constantly changing environment, animals have evolved attention-like processes to effectively filter the incoming sensory stream. These attention-like processes, in turn, are modulated by memory. The neurobiological nature of how attention, action selection and memory are inter-connected is unknown. We describe here new phenotypes of the memory mutant radish in the fruit fly Drosophila.
Comprehensive modeling of microRNA targets predicts functional non-conserved and non-canonical sites.
3 hours ago
ABSTRACT: MirSVR is a new machine learning method for ranking microRNA target sites by a down-regulation score. The algorithm trains a regression model on sequence and contextual features extracted from miRanda-predicted target sites. In a large-scale...
Genomic acquisition of a capsular polysaccharide virulence cluster by non-pathogenic Burkholderia isolates.
ABSTRACT: BACKGROUND: Burkholderia thailandensis is a non-pathogenic environmental saprophyte closely related to Burkholderia pseudomallei, the causative agent of the often fatal animal and human disease melioidosis. To study B. thailandensis genomic variation,...
Construction of a large extracellular protein interaction network and its resolution by spatiotemporal expression profiling.
4 hours ago
Extracellular interactions involving both secreted and membrane-tethered receptor proteins are essential to initiate signaling pathways that orchestrate cellular behaviors within biological systems. Due to the biochemical properties of these proteins and their...
Sentinel Node Biopsy in Squamous-Cell Carcinoma of the Anal Canal.
5 hours ago
BACKGROUND: Radiochemotherapy is the standard treatment for patients with carcinoma of the anal canal. Therefore, a surgical specimen is not usually obtained. Inguinal lymph node metastases cannot be accurately predicted by either clinical examination or imaging...
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Prokariotic Cell Collection in Denmark
Nov 6 2009
I would like to know about a prokariotic cell collection in Denmark. Is there a cell bank in this country? I need a Lactobacillus strain for a fermentation assay and this information about the bank is very helpful for me.
Request for Entries
Oct 16 2009
Ask the Experts is your chance to get the answers to questions on applications, materials, methods, processes, and technologies. Email you question to bst_web@advantagemedia.com, and the editors of Bioscience Technology will find an appropriate expert to answer it. Watch this space in the future to see the questions your colleagues are posting.
Physical activity can reduce the genetic predisposition to obesity by 40 percent
1 hour ago
Tracking marine animal travel
Starvation keeps sleep-deprived fly brain sharp
Mosquitoes use several different kinds of odor sensors to track human prey
Success stops drug trial
Tenet completes tender offer for senior notes
Benefits seen for high-risk women in ovary removal
Gilson announces the launch of PIPETMAN.EU
Aug 20 | News
Beckman Coulter Launches New Data Manager REMISOL Advance v1.4
Aug 16 | News
Beckman Coulter Signs Record Deal to Provide Integrated Testing Solutions to CML Healthcare, a Leading Laboratory Services Provider in Ontario, Canada
Aug 5 | News
Beckman Coulter Exhibits More Solutions for Attendees of 2010 AACC/ASCLS Annual Meeting and Clinical Lab Expo
Jul 26 | News
Merck KGaA Completes Millipore Acquisition and Launches New EMD Millipore Division
Jul 23 | News
Thermo Fisher Scientific and Intrinsic Bioprobes Announce Alliance in Mass Spectrometric Immunoassay (MSIA) Workflow Development
Jul 21 | News
Core knowledge of tree fruit expands with apple genome sequencing
Aug 29
First genetic link to common migraine exposed
Scientists say natural selection alone can explain eusociality
Aug 25
Study shows deepwater oil plume in Gulf degraded by microbes
Aug 24
Study predicts massive impact of drought tolerant maize in Africa
1 hour ago | News
Preventive cancer surgeries save women's lives
2 hours ago | News
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Viewing SureFocus Slides
Jun 11
A demonstration of SureFocus Microscope Slides in the review of AFB Smears. SureFocus Slides are a patent-pending breakthrough in tuberculosis detection, as their fluorescent staining circle remains visible during review, Fluorescence Microscopy.
Allen Institute for Brain Research
Oct 14 2009
Discussed in this interview are both the mouse brain project and the human cortex project with an emphasis on the importance of these projects to neuroscience research.