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Bringing the Cell Image into Focus
Nov 2 2010
Improvements in transmission electron microscope (TEM) technology increase the power of this imaging tool for the study of cell biology.
Finding a Cure for Spinal Cord Injury with On-Demand LIMS
Oct 25 2010
The Miami Project to Cure Paralysis finds an on-demand laboratory information management system (LIMS) helps to accelerate discovery in its HCS projects.
Saving Cells: Image Processing for Improved Viability, Part II: Iterative Deconvolution
3D light microscopy and deconvolution provide a means to investigate 3D structure, providing near-confocal quality images without the temporal requirements or potentially damaging phototoxicity associated with other 3D imaging technologies. This article is Part II in a series regarding viability, resolution improvement, and measurement in fluorescence imaging. Part I focused on spectral unmixing.
Saving Cells: Image Processing for Improved Viability
Sep 22 2010
This article is Part I of a two-part series regarding viability, resolution improvement, and measurement in fluorescence imaging. Part II will focus on deconvolution.
Evaluation of a New Nano-Type UV-Vis Spectrophotometer
Mar 3
Analysis of one- to four-microliter size samples for nucleic acids has become routine in many life science laboratories. However, until now, available instruments require considerable manipulation of the instrument and sample; some require manually recording the data. The user must typically lower and raise the arm manually, then wipe the sample manually from the target after each analysis. And fiberoptics used in some of these instruments are subject to deterioration.
Production of Recombinant Proteins and Monoclonal Antibodies in Hollow Fiber Bioreactors
Jan 25
While well-understood, robust and convenient, classical batch-style 2-D culture on non-porous supports or 3-D suspension culture in other devices are really not very biologically relevant models. Cell culture conditions can affect the quality of the antibody or protein produced.
Selecting Robots for Use in Drug Discovery and Testing
Dec 6 2010
Drug discovery and testing, with their need for speed, repeatability and verification, are ideally suited to benefit from robot automation. It is therefore not surprising that robots have been at the forefront of automation developments in both these areas.
HP Scalable Network Storage Systems for Life Sciences
Sep 13 2010
Life sciences research today is advancing exponentially, each step bringing us closer to the realization of truly personalized medicine–preventive care and treatments designed specifically for each individual. In the near future, PCPGM healthcare researchers expect to be able to use predictive genetic testing to create custom treatment plans for individuals and deliver dramatic improvements over today’s one-size-fits-all approach. But research capabilities are only part of the equation; current storage and operating capacities must also evolve to accommodate ever-expanding amounts of data before the goal of personalized medicine can be realized.
Using the Tecan Genesis Workstation to Automate a Cytometric Bead Array (CBA) Immunoassay
Mar 11 2010
The poster describe the process involved in automating a Cytometric Bead Array (CBA) immunoassay developed to measure relative concentrations of serum antibodies against Tetanus (TT), Sperm Whale Myoglobin (SWM) and Keyhole Limpet Hemocyanin (KLH) in KLH-immunized volunteers.
Ensuring Quality in Assays Performed with Automated Liquid Handlers
Feb 2 2010
The focus of this presentation is to highlight the need of ensuring quality in important assays performed with automated liquid handlers. Nearly all assays performed within a laboratory are volume-dependent. In turn, all concentrations of biological and chemical components in these assays, as well as the associated dilution protocols, are volume-dependent. Because analyte concentration is volume-dependent, an assay’s results might be falsely interpreted if liquid handler variability and inaccuracies are unknown or if the system(s) go unchecked for a long period.
Inkjet System for Protein Crystallography
Feb 1 2010
X-ray crystallography is used routinely by scientists to obtain the three dimensional structure of a biological molecule of interest.Such information can be used to determine how a pharmaceutical interacts with a protein target and what changes might improve functionality. However, the crystallization of macromolecules still remains a serious hindrance in structural determination despite impressive advances in screening methods and technologies.
Attention Deficit & Hyperactivity in a Drosophila Memory Mutant
Nov 9 2009
Action selection is modulated by external stimuli either directly or via memory retrieval. In a constantly changing environment, animals have evolved attention-like processes to effectively filter the incoming sensory stream. These attention-like processes, in turn, are modulated by memory. The neurobiological nature of how attention, action selection and memory are inter-connected is unknown. We describe here new phenotypes of the memory mutant radish in the fruit fly Drosophila.
PrP-specific camel antibodies with the ability to immunodetect intracellular prion protein.
20 hours ago
Viewpoint: Are the research ethics committees working in the best interests of participants in an increasingly globalized research environment?
21 hours ago
Viewpoint: A method to estimate the cost in lives of ethics board review of biomedical research.
Commentary: Systems, rules and the costs of being ethical - a response to D. Chalmers and to S. Whitney and C. Schneider.
more JOURNAL ARTICLES >>
Prokariotic Cell Collection in Denmark
Nov 6 2009
I would like to know about a prokariotic cell collection in Denmark. Is there a cell bank in this country? I need a Lactobacillus strain for a fermentation assay and this information about the bank is very helpful for me.
Request for Entries
Oct 16 2009
Ask the Experts is your chance to get the answers to questions on applications, materials, methods, processes, and technologies. Email you question to bst_web@advantagemedia.com, and the editors of Bioscience Technology will find an appropriate expert to answer it. Watch this space in the future to see the questions your colleagues are posting.
WellPoint CEO received 3 percent raise last year
8 hours ago
Scientists lack complete answers on radiation risk
9 hours ago
Cigna CEO sees 2010 pay jump in first year on job
10 hours ago
Kidney cancer patients who have partial organ removal are healthier
12 hours ago
TSX-listed corporate dividends and di stributions declared March 18, 2024
TSX-listed corporate dividends and distributions declared March 18, 2024
European committee OKs Merck, Teva contraceptive
13 hours ago
GE Healthcare plans big leaps in cardiac care with small, affordable innovative solutions from India
Mar 17 | News
Danaher and Beckman Coulter Announce Early Termination of HSR Act Waiting Period In Connection With Tender Offer
Mar 10 | News
春风送温暖 健康到基层 GE医疗中国推出“春风计划” 全面启动基层医疗战略
Feb 26 | News
GE Healthcare And Cisco To Offer Hospitals A New Mobility Technology Platform For Improved Patient Flow And Asset Management
Feb 25 | News
Gilson releases the new PLC 2020 Personal Purification System
Feb 10 | News
BD Announces Agreement to Acquire Accuri Cytometers
Feb 8 | News
Millipore Names First Seed Grant Fellow
Jan 29 | News
Enzyme Can Steer Cells or Possibly Stop Them in Their Tracks
19 hours ago
Synthetic bone graft recruits stem cells for faster bone healing
Aug 2 2010
Culturing Automation
Jan 4
Newly discovered role for enzyme in neurodegenerative diseases
Mar 10
Study helps explain how pathogenic E. coli bacterium causes illness
Mar 14
19 hours ago | News
ARF1 Localizes to the Golgi and the Trans-Golgi Network.
Mar 17 | PubGet
The role of JNK in the development of hepatocellular carcinoma.
Proteomic and electron microscopy survey of large assemblies in macrophage cytoplasm.
Lysosomal pH and analysis of the counter ion pathways that support acidification
Mar 16 | PubGet
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Viewing SureFocus Slides
Jun 11 2010
A demonstration of SureFocus Microscope Slides in the review of AFB Smears. SureFocus Slides are a patent-pending breakthrough in tuberculosis detection, as their fluorescent staining circle remains visible during review, Fluorescence Microscopy.
Allen Institute for Brain Research
Oct 14 2009
Discussed in this interview are both the mouse brain project and the human cortex project with an emphasis on the importance of these projects to neuroscience research.