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Live Cell Analysis of Autophagy
Sep 4
Analysis of autophagosome formation using fluorescent cellular imaging and lentiviral biosensors.
Deconstructing 3D Cell Culture
Aug 31
3D culture models offer the potential to significantly reduce drug failure.
Safety Without Sacrifice
Jun 26
Liquid handling ergonomics and performance considerations
ELNs: The Beating Heart of a Scientist’s World
May 22
As ELNs deliver more benefits to researchers, the cost of changing working practice is outweighed by access to high quality, high context collaboration.
Evaluation of a New Nano-Type UV-Vis Spectrophotometer
Mar 3 2011
Analysis of one- to four-microliter size samples for nucleic acids has become routine in many life science laboratories. However, until now, available instruments require considerable manipulation of the instrument and sample; some require manually recording the data. The user must typically lower and raise the arm manually, then wipe the sample manually from the target after each analysis. And fiberoptics used in some of these instruments are subject to deterioration.
Production of Recombinant Proteins and Monoclonal Antibodies in Hollow Fiber Bioreactors
Jan 25 2011
While well-understood, robust and convenient, classical batch-style 2-D culture on non-porous supports or 3-D suspension culture in other devices are really not very biologically relevant models. Cell culture conditions can affect the quality of the antibody or protein produced.
Selecting Robots for Use in Drug Discovery and Testing
Dec 6 2010
Drug discovery and testing, with their need for speed, repeatability and verification, are ideally suited to benefit from robot automation. It is therefore not surprising that robots have been at the forefront of automation developments in both these areas.
HP Scalable Network Storage Systems for Life Sciences
Sep 13 2010
Life sciences research today is advancing exponentially, each step bringing us closer to the realization of truly personalized medicine–preventive care and treatments designed specifically for each individual. In the near future, PCPGM healthcare researchers expect to be able to use predictive genetic testing to create custom treatment plans for individuals and deliver dramatic improvements over today’s one-size-fits-all approach. But research capabilities are only part of the equation; current storage and operating capacities must also evolve to accommodate ever-expanding amounts of data before the goal of personalized medicine can be realized.
Using the Tecan Genesis Workstation to Automate a Cytometric Bead Array (CBA) Immunoassay
Mar 11 2010
The poster describe the process involved in automating a Cytometric Bead Array (CBA) immunoassay developed to measure relative concentrations of serum antibodies against Tetanus (TT), Sperm Whale Myoglobin (SWM) and Keyhole Limpet Hemocyanin (KLH) in KLH-immunized volunteers.
Ensuring Quality in Assays Performed with Automated Liquid Handlers
Feb 2 2010
The focus of this presentation is to highlight the need of ensuring quality in important assays performed with automated liquid handlers. Nearly all assays performed within a laboratory are volume-dependent. In turn, all concentrations of biological and chemical components in these assays, as well as the associated dilution protocols, are volume-dependent. Because analyte concentration is volume-dependent, an assay’s results might be falsely interpreted if liquid handler variability and inaccuracies are unknown or if the system(s) go unchecked for a long period.
Inkjet System for Protein Crystallography
Feb 1 2010
X-ray crystallography is used routinely by scientists to obtain the three dimensional structure of a biological molecule of interest.Such information can be used to determine how a pharmaceutical interacts with a protein target and what changes might improve functionality. However, the crystallization of macromolecules still remains a serious hindrance in structural determination despite impressive advances in screening methods and technologies.
Attention Deficit & Hyperactivity in a Drosophila Memory Mutant
Nov 9 2009
Action selection is modulated by external stimuli either directly or via memory retrieval. In a constantly changing environment, animals have evolved attention-like processes to effectively filter the incoming sensory stream. These attention-like processes, in turn, are modulated by memory. The neurobiological nature of how attention, action selection and memory are inter-connected is unknown. We describe here new phenotypes of the memory mutant radish in the fruit fly Drosophila.
Red Meat Consumption and Mortality: Results From 2 Prospective Cohort Studies
Mar 16
BACKGROUND: Red meat consumption has been associated with an increased risk of chronic diseases. However, its relationship with mortality remains uncertain. METHODS: We prospectively observed 37 698 men from the Health Professionals Follow-up Study (1986-2008)...
Structural analysis of eyespots: dynamics of morphogenic signals that govern elemental positions in butterfly wings.
Mar 15
ABSTRACT: BACKGROUND: To explain eyespot colour-pattern determination in butterfly wings, the induction model has been discussed based on colour-pattern analyses of various butterfly eyespots. However, a detailed structural analysis of eyespots that can serve as...
Editorial: Meeting the health care needs associated with poverty, homelessness and social exclusion: the need for an interprofessional approach.
Mar 14
Commentary on Kwong E, Lau A, Lee R & Kwan R (2011) A pressure ulcer prevention programme specially designed for nursing homes: does it work? Journal of Clinical Nursing 20, 2...
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Prokariotic Cell Collection in Denmark
Nov 6 2009
I would like to know about a prokariotic cell collection in Denmark. Is there a cell bank in this country? I need a Lactobacillus strain for a fermentation assay and this information about the bank is very helpful for me.
Request for Entries
Oct 16 2009
Ask the Experts is your chance to get the answers to questions on applications, materials, methods, processes, and technologies. Email you question to bst_web@advantagemedia.com, and the editors of Bioscience Technology will find an appropriate expert to answer it. Watch this space in the future to see the questions your colleagues are posting.
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5 hours ago
Inflammation Marker Linked to Increased Risk for Death From Cancer in Korean Men
8 hours ago
Ultrafiltration may not be best approach for heart failure patients
11 hours ago
Amyris trims 3Q loss on lower operating costs
15 hours ago
News Summary: Pfizer rheumatoid arthritis drug
Calif. considers labeling requirement for GMO food
16 hours ago
PerkinElmer and TIBCO Software Announce Strategic Alliance for TIBCO Spotfire Data Visualization and Discovery
Sep 17 | News
Accelrys Announces Purchase of Cloud-based HEOS Drug Discovery Information Management Technology from SCYNEXIS
May 22 | News
Agilent Technologies and FDA Collaborate to Improve Testing for Salmonella
Mar 21 | News
Cresset Announces the Opening of 4th Design a Molecule Competition
Mar 20 | News
Lonza Signs Light Path Discovery Agreement with LegoChem Biosciences to Provide Pre-clinical Material of Novel Therapeutic Compound
Mar 7 | News
Corning Launches Label-free Cellular Profiling Service for Drug Discovery
Feb 2 | News
Fluidigm and AH Diagnostics Sign Scandinavian Distribution Deal
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Epigenetics
Aug 30
Hank & his clone Circus Hank explain the power of epigenetics, which studies the factors that determine how much or whether some genes are expressed in your body.
Futures In Biotech 93: Snyder's Omics
May 17
Host: Marc Pelletier Co-Host: Andre Nantel, Ph.D. The technologies that our guest has developed are playing an important role in changing the world, not like the car, the microwave and the cell phone, but as in Drs. Flox, McCoy, and Crusher. Guest: Dr. Michael Snyder We invite...