Articles

Hollow Fiber Cartridge/Pump System

Tue, 01/21/2003 - 4:55am
The FiberCell™ Quartet Pump features four independently controlled pumping stations that will accommodate up to four cartridges simultaneously (four small, four medium or two large cartridges). The pumps offer ten pre-set flow rates ranging from 2.5 ml/min to 90 ml/min. Each pump head can be set for optimal flow rates and each cartridge is connected via silicone tubing to a separate cell culture medium reservoir, thereby eliminating the possibility of cross-contamination. FiberCell cartridges utilize hollow fibers with MWCOs ranging from 5K Daltons through .2 μm to provide growth surfaces for cell culture while dialyzing away cell waste and cytokines. Secreted proteins and antibodies concentrate in the small volume of the extracapillary space. Flow path assemblies are pre-sterilized for easy setup. Microprocessor-controlled positive displacement pumps insure long cartridge life and move nutrients and waste across the fibers. The Solo Pump is assembled with a single cartridge and offers ten preset flow rates ranging from 2.5 l/min to 90 ml/min. Reservoir cap assemblies, including tubing and stainless steel media delivery tubes, are available in capacities of 33 mm (for media packaged in glass bottles) and 38 mm (for media packaged in plastic bottles) and can be autoclaved.

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