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Scientists Find Brain Cells with 100+ Unique Mutations

March 4, 2024 10:18 am | by Scripps Research Institute | News | Comments

In a new study, scientists are the first to sequence the complete genomes of individual neurons and to produce live mice carrying neuronal genomes in all of their cells.

A New Way to Discover DNA Modifications

March 1, 2024 10:30 am | by Anne Trafton, MIT News Office | News | Comments

A new technique offers a systematic approach to discovering unknown epigenetic marks and...

Genetic Underpinnings of Widespread Disease Revealed by Scientific Team

February 24, 2024 10:43 am | by Yale University | News | Comments

A global team of scientists has created the first cross-species genomic comparison of the 20...

Individuals' Medical Histories Predicted by Their Noncoding Genomes

February 10, 2024 10:21 am | by Stanford University | News | Comments

Identifying mutations in the control switches of genes can be a surprisingly accurate way to...

Researchers Identify Striking Genomic Signature Shared by 5 Types of Cancer

February 5, 2024 10:38 am | by NIH/National Human Genome Research Institute | News | Comments

Researchers have identified a striking signature in tumor DNA that occurs in five different types of cancer. They also found evidence that this methylation signature may be present in many more types of cancer. The specific signature results from a chemical modification of DNA called methylation, which can control the expression of genes like a dimmer on a light switch.

Scientists Map Bedbug Genome, Follow Pest Through NYC Subway

February 3, 2024 10:48 am | by Verena Dobnik, Associated Press | News | Comments

Scientists have mapped the genome of bedbugs in New York City, then traced fragments of the nefarious pests' DNA through the subway system.

Mapping Regulatory Elements

February 1, 2024 9:37 am | by Larry Hardesty, MIT News Office | News | Comments

Researchers describe a new technique for systematically but efficiently searching long stretches of the genome for regulatory elements. And in their first application of the technique, they find evidence that current thinking about gene regulation is incomplete.

Head Shape and Genetics Augment Understanding of Rattlesnake Species

January 28, 2024 11:31 am | by University of Illinois Urbana-Champaign | News | Comments

Using head shape and genetic analyses, new research challenges the formerly designated subspecies within the western rattlesnake species. These findings have important implications for ecological conservation efforts across the United States and could provide the basis for new species designations.

Faster Drug Discovery?

January 28, 2024 11:05 am | by Rob Matheson, MIT News Office | News | Comments

Genometry has commercialized a high-throughput gene-expression assay, which operates at a fraction of the cost of conventional methods. It does so by using measurements of 1,000 genes to accurately and quickly estimate the activity of all the 20,000 or so genes expressed in a cell.

New Way to Detect Human-Animal Diseases Tested in Lemurs

January 27, 2024 11:31 am | by Duke University | News | Comments

Advances in genetic sequencing are uncovering emerging diseases in wildlife that other diagnostic tests can’t detect.

Food Safety Consortium to Tackle Foodborne Illness

January 27, 2024 9:47 am | by Bevin Fletcher, Associate Editor | News | Comments

Bio-Rad Laboratories Inc., a life science research and clinical diagnostic products manufacturer has joined IBM Research and Mars Inc. in the Consortium for Sequencing the Food Supply Chain. The consortium is harnessing the power of genomics and informatics to study microbiomes in food to help prevent contamination and foodborne illness at any step in the food supply chain.

Largest Prehistoric Marine Crocodile Discovered in Tunisia

January 21, 2024 9:47 am | by Greg Watry, Digital Reporter | News | Comments

Located in southern Tunisia, Tataouine is a desert province located in a region marred by political conflict. In 2009, a team led by Univ. of Bologna’s Prof. Federico Fanti began working to unearth the fossilized remnants of the region’s prehistoric ecosystem

New Tool Puts Accurate DNA Analysis in Fast Lane

January 19, 2024 9:43 am | by Rice University | News | Comments

Scientists have developed a tool to speed the design of molecular diagnostics that depend on the specific recognition of pathogen DNA and RNA.

Genomics, Cannabidiols Drive Epilepsy Research

January 19, 2024 8:46 am | by Bevin Fletcher, Associate Editor | Articles | Comments

Scientists recently converged in Philadelphia for the American Epilepsy Society’s (AES) 69th Annual Meeting, touting new studies and insights in the field of epilepsy. Researchers discussed new findings, including personalized medicine, and the promise of Cannabidiol in human and animal studies.

Dog Domestication May Have Increased Harmful Genetic Changes

January 12, 2024 10:18 am | by UCLA | News | Comments

The domestication of dogs may have inadvertently caused harmful genetic changes, a new study suggests.

Scientists Crack Wheat Genome

January 12, 2024 9:48 am | by Bevin Fletcher, Associate Editor | News | Comments

Using bioinformatics tools and advanced software, a group of scientists have been able to sequence about 90 percent of the complex genome of bread wheat.

Gene Editing Improves Vision in Rats with Inherited Blindness

January 8, 2024 10:05 am | by Cedars-Sinai Medical Center | News | Comments

A new technique that has the potential to treat inherited diseases by removing genetic defects has been shown for the first time to hinder retinal degeneration in rats with a type of inherited blindness.

Neanderthal Genes Gave Modern Humans an Immunity Boost, Allergies

January 8, 2024 9:53 am | by Cell Press | News | Comments

When modern humans met Neanderthals in Europe and the two species began interbreeding many thousands of years ago, the exchange left humans with gene variations that have increased the ability of those who carry them to ward off infection. This inheritance from Neanderthals may have also left some people more prone to allergies.

Cancer-Suppressing Gene May Cause Colorectal Cancer Spread

January 5, 2024 8:33 am | by Ryan Bushey, Associate Editor | News | Comments

University of Missouri School of Medicine researchers discovered that a cancer-suppressing gene called Sprouty2 may induce the growth of certain forms of colorectal cancer.

Study Identifies Liver-Generated Hormone that Regulates 'Sweet Tooth'

January 4, 2024 9:06 am | by University of Iowa | News | Comments

Previous research explains how certain hormones affect appetite; however, these hormones do not regulate any specific macronutrient (carbohydrate, protein, fat) and are produced by organs other than the liver.

Study Uncovers Inherited Genetic Susceptibility Across 12 Cancer Types

January 4, 2024 9:04 am | by Washington University in St. Louis | News | Comments

In a new analysis, researchers have shed light on hereditary elements across 12 cancer types — showing a surprising inherited component to stomach cancer and providing some needed clarity on the consequences of certain types of mutations in well-known breast cancer susceptibility genes, BRCA1 and BRCA2.

Microorganisms in the Womb Set Stage for Diseases

December 31, 2023 8:35 am | by University Hospitals Case Medical Center | News | Comments

Researchers review importance of microorganisms that exist in the gut, suggesting perturbation of the environment during pregnancy, delivery and early infancy could impact the developing baby's early microbiome and set the stage for health problems later in life.

Early-life Exercise Alters Gut Microbes, Promotes Healthy Brain and Metabolism

December 30, 2023 8:41 am | by University of Colorado, Boulder | News | Comments

The human gut harbors a teeming menagerie of over 100 trillion microorganisms.

New Software Can Identify Drug Resistance from Bacterial Genomes

December 22, 2023 9:49 am | by University of Oxford | News | Comments

Scientists have developed an easy-to-use computer program that can quickly analyze bacterial DNA from a patient's infection and predict which antibiotics will work, and which will fail due to drug resistance. The program can analyze the entire genetic code of a bacterium in under 3 minutes, once a bacterial sample has been cultured and its DNA sequenced.

Viral Infections Leave a Signature on Human Immune System

December 16, 2023 9:57 am | by Stanford University | News | Comments

A team of immunologists and informatics experts has identified a distinctive pattern of gene expression that distinguishes people with a viral infection from those with a bacterial infection. The team also identified a second pattern of gene expression that is more specific: It can distinguish the flu from other respiratory infections.

A Year in Biotech & Digital Health

December 16, 2023 8:28 am | by Ryan Bushey, Associate Editor | News | Comments

Bioscience Technology took a look back at the year that was and rounded up the most interesting developments in biotech.

New Technique Reveals Gut Bacteria Diversity

December 15, 2023 10:00 am | by Stanford University | News | Comments

A collaboration between computer scientists and geneticists has produced a novel technique for mapping the diversity of bacteria living in the human gut.

Study Uncovers Hard-to-detect Cancer Mutations

December 15, 2023 9:31 am | by Washington University in St. Louis | News | Comments

New research shows that current approaches to genome analysis systematically miss detecting a certain type of complex mutation in cancer patients’ tumors. Further, a significant percentage of these complex mutations are found in well-known cancer genes that could be targeted by existing drugs, potentially expanding the number of cancer patients who may benefit.

Six Reasons to Add Object Storage to Your Genomics Lexicon

December 15, 2023 8:42 am | by Claire Giordano, Senior Director of Emerging Storage Markets, Quantum | Articles | Comments

Object storage has been around for some time, but the technology is now gaining more and more traction in life sciences. This article outlines six reasons that organizations should add object storage to their genomics lexicon.

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