Hollow Fiber Cell Culture

FiberCell's SOLO Hollow Fiber Cell Culture System is a closed continuous flow bioreactor that can cost-effectively achieve cell densities over 10⁸ ml and produce 100 mg to 2 grams of protein. Various molecular weight cutoff (MWCO) hollow fiber cartridges can be used to maximize selection and yield of secreted proteins. Appropriate for both adherent and suspension cell lines, the system includes a single microprocessor-controlled pump that can produce flow rates from 2.5 to 75 ml/min and is designed to fit easily in most CO₂ incubators. The SOLO can support all types and sizes of hollow fiber cartridges from research-scale to 1.2 m² production-scale. In addition to monoclonal antibody production, other applications and protocols are available for producing Recombinant Proteins, Adenovirus Vectors, Cytokines and Growth Factors, Endothelial Cell Culture and Artificial Organ research.