96-Well Ultrafiltration Systems

New 96-well ultrafiltration plate and assembly, for protein applications, includes the MultiScreen® filter assembly with Ultracel-PPB membrane for plasma protein binding assays and the MultiScreen filter plate with Ultracel-10 membrane for the concentration and purification of biological solutions. Operated by centrifugation, these 96-well filter plates and assemblies incorporate proprietary low-binding Ultracel membrane. The filter assembly is optimized for in-vitro plasma protein binding assays. The assembly includes a receiver plate and extended centrifugal lid. Stringently QC-released around the near retention (>99.5;%) of serum albumin proteins, the filter assembly provides a pre-qualified platform for the quantitative separation of proteins in bound versus free drug applications. The filter plate is for sample purification, concentration and desalting of biological solutions. This low protein binding 96-well filter plate is QC-released and lot tested for greater than 95% well to well retention of cytochrome c.