Cell Function Genomic Arrays

OriGene® SmartArray™ gene chips contain pre-selected groups of genes in the form of PCR fragments (400-700 bp). These selected genes are functionally related and are involved in the same regulatory pathway. For example, SmartSet 5 contains genes involved in signal transduction: G proteins, G protein-coupled receptors, and regulators for G protein. These focused chips allow users to identify candidate genes whose products interact and/or act in concert to control cellular functions. Each PCR fragment was meticulously selected so that it has greater than 85% homology with its mouse counterpart, yet does not hybridize with other homologous members from the same gene family. SmartArray is optimized for the radioisotopic (³³P) method of detection and may be stripped and re-used up to three times.