Human Breast Cancer Tissue Microarrays

Human breast cancer tissue microarrays (TMA) are offered for high throughput screening of the in situ gene expression for target validation. The breast cancer TMAs may be used for differential gene expression profiling. A variety of tumors and different grades of tumors are represented on a single slide. Paired normal and abnormal samples from the same patient are also represented in the TMAs. Hence, gene expression can be correlated with the normal breast tissue and breast cancer tissue, or with different stages of cancer development. The tissues are fixed in neutral buffered formalin, embedded in paraffin, and sectioned at approximately 3-5 μm section thickness. The tissues are validated for use in immunohistochemistry and may also be used in in situ hybridization assays.