SPR-MS Proteomics Research System

The Biacore®3000; SPR-based (surface plasmon resonance) research system, for the study of biomolecular interactions, has been made more powerful through the incorporation of automated and increased capacity recovery functionality and direct MALDI target deposition for further analysis by MALDI-TOF, or even TOF/TOF mass spectrometry. SPR technology provides the means of detecting, capturing and delivering valuable proteins without any labeling or modification. Subsequent sequencing by mass spectrometry is facilitated by automated sample preparation including an option to deposit sample direct onto the MALDI plate. This means that researchers now have ready access to critical functional SPR data on protein-protein or protein-peptide interactions, combined directly with mass spectrometric identification and characterization of novel proteins.