Articles
Universal DNA Microarray For Whole Genome Expression Profiling
Wed, 04/09/2024 - 5:28am
Agilix's GenCompass is a universal DNA microarray-based platform that provides comprehensive coverage across all genomes. It allows high throughput gene expression profiling of any organism with quality control at each step in the process. GenCompass begins with a novel 4,096 element universal microarray composed of short oligonucleotide probes (containing all possible hexamer DNA sequences). The GenCompass process combines the repetitive use of this fixed element array with molecular biology techniques, including the use of restriction enzymes and DNA adapters to obtain hundreds of thousands of sequence tags (GenTags) 14 nucleotides in length. Whether an organism of interest is fully sequenced, partially sequenced or unsequenced, the expression of its genes can be studied via comparison with other reference organisms, to discover gene function and genes of interest.