Testing Method for RNA in Fixed Tissue Samples

Using qNPA (quantitative Nuclease Protection Assay) technology, researchers can quantitate RNA expression for up to 16 targets simultaneously in FFPE tissue sections without the need for extraction or target amplification. Whole assay CVs are 10 percent or less and the qNPA method has been tested successfully on tissue blocks up to 15 years old. The sensitivity provided is sufficient to measure any gene, including low abundant genes. Researchers are also able to select a set of genes for simultaneous evaluation, a critical step in identifying the most promising drug compounds to treat complex, multi-factorial diseases.