Product Releases

Multiplex Cell-Based Assays

Tue, 02/13/2007 - 10:36am

The FDSS6000 imaging-based plate reader collects orthogonal data while performing an assay. For example, library compounds that either quench fluorescence of a given dye or autofluoresce are identified using both Fura-2 AM and Fluo-4 AM loaded cells. Further, calcium mobilization and membrane potential responses are simultaneously collected in the same cells using Fura-2 AM and membrane potential dyes. Esterase activity, indicating cell integrity, is measured using Calcein Blue-AM while calcium mobilization data (Fluo-4 AM loaded cells) is collected.


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