PCR Purification System (10625)

The Agencourt AMPure PCR Purification System (Beckman Coulter, Inc., Fullerton, CA) has been validated for target preparation with the Genome-Wide Human SNP Array 5.0 by Affymetrix, Inc. (Santa Clara, CA). The SNP Array 5.0 is a comprehensive single array for genetic studies, and it is used by researchers to identify and understand complex conditions such as autism, autoimmunity, bipolar disease, cancer, diabetes and heart disease. The system is based on the SPRI (Solid Phase Reversible Immobilization) (Agencourt Corp. Beverly, MA) paramagnetic bead-based nucleic acid purification technology, which is used in automated purification methods available on Beckman Coulter laboratory workstations. The SPRI beads bind the PCR amplicons and draw them out of solution, allowing contaminants to be easily rinsed away.