2D Protein Gel Analysis Software (11125)

Dymension software for automated 2D protein gel analysis includes the Common Spot Outlines algorithm for automatic detection of the presence or absence of proteins in large data sets. This generates data that, with minimal manual post-editing, can be statistically analyzed to identify the correct proteins for downstream research. The algorithm in Dymension that produces common spot outlines first warps all the gel images in an experiment together to create an averaged gel image, and then performs detection on this image. These common spot outlines are overlaid onto each gel in the experiment’s series. With this method, each spot exists on every gel. Results are less affected by noise and are more representative of the common features of the underlying data.