Case-Control Whole Genome Database

The iControlDB genotyping control repository is offered for researchers conducting case-control whole-genome association studies. Case-control studies compare groups of patients who already have a disease (case) with a group of patients without the disease (control) to identify risk factors that may contribute to a medical condition. Located at www.illumina.com/iControlDB, the database provides an efficient way for investigators to obtain control samples, allowing them to focus resources on genotyping disease samples. Combined with the database of Genotype and Phenotype (dbGaP), the scientific community can now access nearly 10,000 control samples that have been donated by researchers using proprietary technology for single-nucleotide polymorphism (SNP) genotyping. All data uploaded to iControlDB are subject to a rigorous quality control process. To date, control samples uploaded to this database have an average call rate of 99.6 percent.