The FlowSyn Auto-LF loop filling module from Uniqsis is a module that allows chemists to automatically perform in sequence combinatorial flow chemistry experiments. Each experiment can be run under different conditions and utilize a different set of reagents or monomers. Incorporating a separate liquid handler and fraction collector, FlowSyn Auto-LF enables sample loop filling in preparation for the next experiment to take place before the current experiment has finished, thereby reducing overall reaction runtimes. Additionally, the module has no injection ports to leak or block, and the fully integrated robust wash protocols minimise the risk of cross-contamination. Sampler calibration ensures that reagent ‘plugs’ are positioned precisely in the loops to ensure volumetrically accurate partial loop filling that avoids wasting starting materials when performing reactions with different stoichiometries. The PC software included with FlowSyn Auto-LF makes real-time reaction monitoring and data logging straightforward. Data can be saved as a log file for each experiment to give an audit trail. The Uniqsis FlowSyn is a compact integrated continuous flow reactor system designed for safe and efficient operation. The FlowSyn range includes models for performing single or multiple homogeneous or heterogeneous reactions, either manually or automatically.

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