New Chip Technology Provides Rapid and Sensitive Quantitation of Small Molecules
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Protea Biosciences Group, Inc. presented a new Chip-Based Technology at the Pittsburgh Conference (Pittcon), in New Orleans, LA.
This nanopost array technology, called REDIchip (Resonance-Enhanced Desorption Ionization), was invented in the laboratory of Akos Vertes, Ph.D.., Department of Chemistry, George Washington University. The chip is designed to be used for mass spectrometric analysis on MALDI platforms without the need for matrix.
“REDIchips provide a solution to pharmaceutical researchers interested in detecting small molecules without the common interference of chemical matrix. The ability to reproducibly detect and quantitate small molecules is made possible due to the structured nanopost array (NAPA) present in the silicon chip,” stated Haddon Goodman, Imaging Program Manager. He continued,“the REDIchip enables more sensitive quantitation for small molecules than traditional workflows using a robust and reproducible matrix-free environment.”
Protea’s REDIchip technology features were presented at Pittcon and the commercial product is expected to be available at the upcoming American Society for Mass Spectrometry (ASMS) conference this spring. The commercial product will be compatible with a variety of MALDI systems, and it will allow rapid and reproducible sample analysis of small molecules by laser desorption ionization.
Protea Biosciences Group Inc., (304) 292.2226, www.proteabio.com
