The Future of the FDA: Operating in an Electronic World

Oct 12

Acording to an Axendia reseach study, the FDA is currently shifting its organizational and technology infrastructures to facilitate electronic interactions with the companies it regulates.

Tissue Microarrays - Opening up new opportunities in the Therapeutics sector

Oct 12

Tissue Microarray has become a pivotal cog in the wheel for high throughput studies and is an integral part in the validation process for screening results from discovery platforms for expression studies using various approaches.

Translational Informatics for Systems Biology

Oct 12

A study in which IO Informatics' Sentient software has been applied to integrating and linking a customer's multiple data streams.

De Novo Formula Generation with Sub-ppm Confidence

Oct 12

Novel technology embodied in the micrOTOF allows precise measurement of both accurate mass and True Isotopic Pattern (TIP) over a wide dynamic range, allowing for the implementation of an open access system.

ADP-Glo™: An Ideal Approach to Monitor the Activity of Protein Kinases and Beyond

Oct 16

Because of its versatility (alltypesofsubstrates), robustness (Z’>0.8), rapidperformance, and its ease of use, the luminescence based Kinase Glo® assay platform has gained wide acceptance in many drug screening programs for protein kinase inhibitors.

A Cell-Based, Microplate Format, DELFIA Assay for Determination of the Activation of MAP KinaseSofia

Oct 16

Mitogen-activated protein kinases(MAPK) are activated in response to extracellularsignals or cellular stress. We have set up a cell-based DELFIA®Time-Resolved Fluorescence assay to test compounds or conditions for their ability to modulate cellular stress by the activation of MAPK.

Cell Based Assays for Studying the Effects of Cytotoxic Agents

Oct 16

Apoptosis, DNA fragmentation and cell proliferation are important parameters when studying live cell function, especially, when the effects of cytotoxic agents are under study.

Life course variations in the associations between FTO and MC4R gene variants and body size

10 hours ago

The timing of associations between common genetic variants for weight or BMI across the life course may provide insights into the aetiology of obesity. We genotyped variants in FTO (rs9939609) and near MC4R (rs17782313) in 1240 men and 1239 women born in 1946 and participating...

Left ventricular systolic dysfunction by itself does not influence outcome of atrial fibrillation ablation

10 hours ago

AimsThe objective of the study was to analyse the influence of left ventricular (LV) ejection fraction (EF) on the outcomes of atrial fibrillation (AF) ablation after a first procedure. Pre-procedural predictors of recurrences after AF ablation can be useful for patient...

Midterm 'super-response' to cardiac resynchronization therapy by biventricular pacing with fusion: insights from electro-anatomical mapping

10 hours ago

AimsSome authors recommend avoiding fusion with left ventricular (LV) intrinsic depolarization during cardiac resynchronization therapy (CRT). If fusion is still present during optimized biventricular (Biv) pacing and its long-term effects on the response to CRT are currently...

Asymmetric Direct Aldol Reactions Catalyzed by a Simple Chiral Primary Diamine–Brønsted Acid Catalyst in/on Water

10 hours ago

The direct asymmetric aldol reaction catalyzed by the simple and commercially available chiral primary diamines, (1S,2S)-1,2-diphenylethane-1,2-diamine and (1R,2R)-1,2-diphenylethane-1,2-diamine, is presented. The catalyst system is a primary amine...

Request for Entries

Oct 16

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