Scientists explain the neurological process for the recognition of letters and numbers

Featured In: Lab Tools

By EurekAlert Monday, July 26, 2024

newsvine diigo google
slashdot
Share
Loading...

"We analyzed the influence of the context given by a word when linking the physical traits of its components to the abstract representations of letters," explains to SINC Nicola Molinaro, main author of the study and researcher of the Basque Research Center on Cognition, Brain and Language (BCBL).

The results, published in Neuropsychologia journal, show that the linguistic context given by a word impacts the way in which single abstract representations of the letters that make it up are accessed, and that such access is partially independent from the physical properties of the stimuli.

"Otherwise, it would not be possible to think that a number can activate the representation of a letter when it is inserted among a string of letters that make up a word (M4T3R14L)," says Molinaro.

"We used numbers that visually resemble letters (1-I, 5-S, 7-T), and we replaced them," states the expert. The words were presented to participants during tenths of milliseconds (imperceptible to consciousness). Then, the correct words where shown so that participants could read them (for example, M4T3R14L - MATERIAL). Control strings including numbers explicitly different to letters (M9T6R26L- MATERIAL) and word identity (MATERIAL- MATERIAL) were also included.

The brain responds in three different ways

While participants read the words in silence, scientists recorded brain potentials associated to events (ERPs), which showed three main effects. The first one is that, over the 150 ms window, identical strings and strings including visually similar numbers, compared to control strings, caused a reduction in positivity, that is, in the ease of recognition.

"This effect shows that in the case of strings with letter-like numbers, the link between the visual physical representations of numbers and the abstract representations of correct letters is made automatically, given the visual overlapping among characters," points out the neuroscientist.

A second effect confirmed, at the 200 ms window, greater negativity for number conditions (M4T3R14L and M9T6R26L). "The brain recognizes that the elements that make up the strings presented unconsciously are in fact numbers, not letters, showing some specificity in the processing despite the initial visual overlapping found in the above component," he assures.

Lastly, 250 ms after the display of strings, the conditions of identity and visually letter-like numbers showed a very similar positive effect, clearly different from the effect caused by the strings with numbers that were visually different from letters (control).

"The global processing of words is very similar for strings that include letters that are properly written and for those including numbers that are visually similar to letters", concludes Molinaro.

SOURCE

Join the Discussion
Rate Article: Average 0 out of 5
register or log in to comment on this article!

0 Comments

Add Comment

Text Only 2000 character limit

Page 1 of 1

Research Exchange

Optical Imaging in Stem Cell Research

Jun 1

Developing sensitive, non-invasive technologies to monitor engraftment in vivo is essential to accelerate the clinical implementation of cell therapies.

Standing Up in a Court of Law

Jun 1

Private forensic testing laboratory ensures data integrity with advanced calibration systems.

Simultaneous Measurement of Multiple Signaling Pathways in Human Leukemias Using Flow Cytometry

May 24

Next generation assays will need to be robust and standardized in order to make the transition from a research procedure to a routine clinical assay. Flow cytometry provides a unique and sensitive method to accomplish these requirements.

Automated Forensic DNA Methods: Relieving the Pain of Validation

Apr 21

Automation can increase a forensics lab's sample processing capacity, but it can also add to the complexity of system verification and validation.

Step up to the MIQE

Mar 30

Over the years, polymerase chain reaction (PCR) has evolved into a readily automated, high throughput quantitative technology. Real-time quantitative PCR (qPCR) has become the industry standard for the detection and quantification of nucleic acids for multiple application, including quantification of RNA levels. But a lack of consensus among researchers on how to best perform and interpret qPCR experiments presents a major hurdle for advancement of the technology. This problem is exacerbated by insufficient experimental detail in published work, which impedes the ability of others to accurately evaluate or replicate reported results.

Fast Optimization of a Multiplex Influenza Identification Panel Using a Thermal Gradient

Mar 30

The year 2009 was marked by the emergence of a novel influenza A (H1N1) virus that infects humans. There is a need to identify the different strains of influenza virus for purposes of monitoring the H1N1 strain pandemic and for other epidemiological and scientific purposes.

Advantages of Monolithic Laser Combiner Technology in Confocal Microscopy Systems

Jan 6

Fluorescence microscopy techniques require a reliable light source at the desired wavelength or wavelengths, with minimal downtime for maintenance and alignment. Lasers are a popular light source, although the alignment and upkeep of laser combiners is a time-consuming prospect for many users.

Size-Exclusion Chromatography for Purification of Biomolecules

Dec 2 2009

Size-exclusion chromatography (SEC) is a popular method to separate biomolecules based on their size. Primarily, it is applied to the separation of biopolymers such as proteins and nucleic acids, i.e. water-soluble polymers.

Using the Tecan Genesis Workstation to Automate a Cytometric Bead Array (CBA) Immunoassay

Mar 11

The poster describe the process involved in automating a Cytometric Bead Array (CBA) immunoassay developed to measure relative concentrations of serum antibodies against Tetanus (TT), Sperm Whale Myoglobin (SWM) and Keyhole Limpet Hemocyanin (KLH) in KLH-immunized volunteers.

Ensuring Quality in Assays Performed with Automated Liquid Handlers

Feb 2

The focus of this presentation is to highlight the need of ensuring quality in important assays performed with automated liquid handlers. Nearly all assays performed within a laboratory are volume-dependent. In turn, all concentrations of biological and chemical components in these assays, as well as the associated dilution protocols, are volume-dependent. Because analyte concentration is volume-dependent, an assay’s results might be falsely interpreted if liquid handler variability and inaccuracies are unknown or if the system(s) go unchecked for a long period.

Inkjet System for Protein Crystallography

Feb 1

X-ray crystallography is used routinely by scientists to obtain the three dimensional structure of a biological molecule of interest.Such information can be used to determine how a pharmaceutical interacts with a protein target and what changes might improve functionality. However, the crystallization of macromolecules still remains a serious hindrance in structural determination despite impressive advances in screening methods and technologies.

Attention Deficit & Hyperactivity in a Drosophila Memory Mutant

Attention Deficit & Hyperactivity in a Drosophila Memory Mutant

Nov 9 2009

Action selection is modulated by external stimuli either directly or via memory retrieval. In a constantly changing environment, animals have evolved attention-like processes to effectively filter the incoming sensory stream. These attention-like processes, in turn, are modulated by memory. The neurobiological nature of how attention, action selection and memory are inter-connected is unknown. We describe here new phenotypes of the memory mutant radish in the fruit fly Drosophila.

Interferon-Gamma Release Assay in the Ascites: Early Hint for Diagnosis of Abdominal Tuberculosis

11 hours ago

We report on a 20-year-old woman with abdominal tuberculosis. Standard microbiological examination of ascites showed no acid-fast bacilli (AFB), and analysis for the Mycobacterium tuberculosis (MTB)-complex DNA by PCR was negative. However, the interferon-γ release assay (IGRA)...

Coverage and Predictors of Adherence to Influenza Vaccination among Spanish Children and Adults with Asthma

11 hours ago

Background Influenza infections are frequently implicated in the exacerbation of asthma. The aim of this study was to assess vaccination coverage among Spanish children and adults with asthma and to describe the factors associated (predictors) with vaccination, using data from...

Persistent Helicobacter canis Bacteremia in a Patient with Gastric Lymphoma

11 hours ago

A 78-year-old man with gastric diffuse large B cell lymphoma presented with persistent Helicobacter canis bacteremia while receiving chemotherapy. An examination of his medical history revealed a close exposure to dogs. The patient recovered after 4 weeks of antibiotic therapy....

Management of Hepatitis B Virus Reactivation in Patients with Hematological Malignancies Treated with Chemotherapy

11 hours ago

Introduction Hepatitis B virus (HBV) reactivation is a major cause of morbidity and mortality in patients with hematological malignancies who receive cytotoxic chemotherapy. We have therefore carried out a prospective observational study out to assess the incidence, prevalence,...

Prokariotic Cell Collection in Denmark

Nov 6 2009

I would like to know about a prokariotic cell collection in Denmark. Is there a cell bank in this country? I need a Lactobacillus strain for a fermentation assay and this information about the bank is very helpful for me.

Request for Entries

Oct 16 2009

Ask the Experts is your chance to get the answers to questions on applications, materials, methods, processes, and technologies. Email you question to bst_web@advantagemedia.com, and the editors of Bioscience Technology will find an appropriate expert to answer it. Watch this space in the future to see the questions your colleagues are posting.

STAY INFORMED: SUBSCRIBE TO

Magazine and E-mail Newsletters

Loading...
E-mail:   

MULTIMEDIA

Video:

Viewing SureFocus Slides

Jun 11

A demonstration of SureFocus Microscope Slides in the review of AFB Smears. SureFocus Slides are a patent-pending breakthrough in tuberculosis detection, as their fluorescent staining circle remains visible during review, Fluorescence Microscopy.

Podcasts:

Allen Institute for Brain Research

Allen Institute for Brain Research

Oct 14 2009

Discussed in this interview are both the mouse brain project and the human cortex project with an emphasis on the importance of these projects to neuroscience research.

Information: