COMPUTER HARDWARE AND SOFTWARE
Amniotic Fluid Yields Alternatives to Embryonic Stem Cells
July 3, 2024 6:06 am | News | CommentsStem cells found in amniotic fluid can be transformed into a more versatile state similar to embryonic stem cells.
LISTED UNDER: GenomicsThe “$1,000 genome” May Cost $100,000 to Understand
May 11, 2024 8:31 am | News | CommentsAdvances in technology have almost lifted the curtain on the long-awaited era of the “$1,000 genome.” However, a price tag of $100,000, by one conservative estimate, is necessary to analyze that genetic data so it can be used in personalized medicine.
LISTED UNDER: GenomicsStudy Maps Hotspots of Genetic Rearrangement
April 6, 2024 5:54 am | News | CommentsResearchers have zoomed in on mouse chromosomes to map hotspots of genetic recombination — sites where DNA breaks and reforms to shuffle genes. The findings of the scientists at the National Institutes of Health and Uniformed Services University of Health Sciences (USU) have the potential to improve the detection of genes linked to disease and to help understand the root causes of genetic abnormalities.
LISTED UNDER: GenomicsDNA 'End-Caps' Lengths are Linked to Diabetes Risk
March 28, 2024 9:57 am | News | CommentsNew evidence has emerged from studies in mice that short telomeres or “caps†at the ends of chromosomes may predispose people to age-related diabetes, according to Johns Hopkins scientists.
LISTED UNDER: GenomicsStructure of DNA Repair Complex Reveals Workings of Cell Motor
March 28, 2024 5:38 am | News | CommentsOver the last years, two teams of researchers at The Scripps Research Institute have steadily built a model of how a powerful DNA repair complex works. Now, their latest discovery provides revolutionary insights into the way the molecular motor inside the complex functions – findings they say may have implications for treatment of disorders ranging from cancer to cystic fibrosis.
LISTED UNDER: GenomicsEpigenomic Research Illuminates Veiled Variants
March 24, 2024 9:26 am | News | CommentsUsing a new mapping strategy, a collaborative team led by researchers at the Broad Institute of MIT and Harvard, Massachusetts General Hospital (MGH), and MIT has begun to assign meaning to the regions beyond our genes and has revealed how minute changes in these regions might be connected to common diseases.
LISTED UNDER: GenomicsMutant Prions Help Foil Harmful Protein Misfolding
March 21, 2024 8:26 am | News | CommentsMisfolded proteins are implicated in many incurable neurological diseases. A new and improved understanding of how naturally occurring variants keep proteins from bunching up and spreading provides more options for developing a treatment than scientists had realized.
LISTED UNDER: Protein AnalysisImaging Technique Provides Rapid, High-definition Chemistry
March 21, 2024 8:16 am | News | CommentsWith intensity a million times brighter than sunlight, a new synchrotron-based imaging technique offers high-resolution pictures of the molecular composition of tissues with unprecedented speed and quality. Carol Hirschmugl, a physicist at the University of Wisconsin-Milwaukee (UWM), led a team of researchers from UWM, the University of Illinois at Urbana-Champaign, and the University of Illinois at Chicago (UIC) to demonstrate these new capabilities.
LISTED UNDER: ImagingUniversity of Rochester Scientists Find a Key to Maintaining Our DNA
March 18, 2024 8:34 am | News | CommentsDNA contains all of the genetic instructions that make us who we are, and maintaining the integrity of our DNA over the course of a lifetime is a critical, yet complex part of the aging process. In an important, albeit early step forward, scientists have discovered how DNA maintenance is regulated, opening the door to interventions that may enhance the body's natural preservation of genetic information.
LISTED UNDER: GenomicsGenes Help Decide When It’s Time to Look for New Food
March 16, 2024 3:05 pm | News | CommentsFor worms, choosing when to search for a new dinner spot depends on many factors, both internal and external: how hungry they are, for example, how much oxygen is in the air, and how many other worms are around. A new study demonstrates this all-important decision is also influenced by the worm's genetic make-up.
LISTED UNDER: GenomicsThird Generation Map of Human Genetic Variation Published
September 8, 2024 7:54 am | News | CommentsAn international consortium published a third-generation map of human genetic variation, called the HapMap, which includes data from an additional seven global populations, increasing the total number to 11 populations. The improved resolution will help researchers interpret current genome studies aimed at finding common and rarer genetic variants associated with complex diseases.
LISTED UNDER: GenomicsCloud Computing Method Greatly Increases Gene Analysis
September 8, 2024 7:37 am | News | CommentsResearchers at the Johns Hopkins Bloomberg School of Public Health have developed new software that greatly improves the speed at which scientists can analyze RNA sequencing data. RNA sequencing is used to compare differences in gene expression to identify those genes that switched on or off when, for instance, a particular disease is present. However, sequencing instruments can produce billions of sequences per day, which can be time-consuming and costly to analyze.
LISTED UNDER: GenomicsAlzheimer's Risk Gene Causes Alterations in Shapes of Brain Protein Deposits
July 15, 2024 8:23 am | News | CommentsResearchers at Mount Sinai School of Medicine have used a newly discovered class of biomarkers to investigate the possibility that the shape of brain protein deposits is different in people with Alzheimer's who have the highest-risk gene type than in those with the condition who have a neutral risk gene type.
LISTED UNDER: Neuroscience | GenomicsNew computational method to uncover gene regulation
April 23, 2024 4:41 am | by University of Manchester | News | CommentsScientists have developed a new computational model to uncover gene regulation, the key to how our body develops – and how it can go wrong.
LISTED UNDER: GenomicsGene Therapy Cures Canines of Inherited Form of Day Blindness
April 21, 2024 10:02 am | News | CommentsVeterinary ophthalmology researchers from the University of Pennsylvania have used gene therapy to restore retinal cone function and day vision in two canine models of congenital achromatopsia, also called rod monochromacy or total color blindness.
LISTED UNDER: Genomics