The new CDM-HD from FiberCell Systems Inc. is a chemically defined, protein free, cGMP compliant serum replacement that permits any basal medium such as DMEM or RPMI to be used without serum.  The serum replacement is designed for the culture of cells at high density, permitting growth in a simplified medium. It is the first serum replacement optimized for hollow fiber bioreactors and other high density cell culture systems. Secreted products, such as monoclonal antibodies, and recombinant proteins are free of contaminating proteins from the medium and can be purified using simpler protocols, increasing net yield in many cases. The serum replacement provides lot-to-lot consistency and is available as a dry powder to make up one liter, and is used at a concentration of 10 percent. An instructional video: www.fibercellsystems.com/CDMHDvideo

FiberCell Systems, Inc., www.fibercellsystems.com