Acoustic Separator Offers Single-Use Format
LISTED UNDER:
Pall Life Sciences' Cadence Acoustic Separator (CAS) applies acoustic wave separation technology in a novel single-use format for the clarification of cell culture bioprocess fluids. The separator delivers robust, reliable cell and protein yields in a closed system without centrifugation, while drastically reducing user cost and risk. It is available for immediate ordering and shipment, and has also been designed to be easily integrated with other Pall Life Sciences products to enable continuous bioprocessing.
The company obtained an exclusive license to acoustic wave separation technology in June 2015 from FloDesign Sonics (FDS). The separator works via acoustic forces that are applied across a countercurrent flow of bioprocess fluid, generating three-dimensional standing waves that trap cells at their nodes. This leads to aggregation and precipitation from suspension, thereby “trapping” the cells for simple extraction. The unit is capable of clarifying many types of biologic products, including recombinant therapeutic proteins and monoclonal antibodies, regardless of the variability in particulate concentrations and cell culture density, turbidity and viability.
The separator is part of the Cadence product portfolio, which features enabling technologies for key unit operations required in the continuous production of monoclonal antibodies and other recombinant proteins. The portfolio leverages the benefits of single-use technologies to feature integrated, end to end biomanufacturing solutions that increase productivity and decrease risk for customers.
Pall Corp., (516) 484-5400, www.pall.com
