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Scientists Observe the Global Motions of an Enzyme Copying DNA

Oct 27 | News

Scientists here have identified how the motions of an enzyme are related to correctly copying genetic instructions, setting the stage for studies that can uncover what happens when DNA copying mistakes are made.

Scanning Electron Microscopes for Forensics

Oct 23 | Products

FEI Company announced the release of two dedicated scanning electron microscopes (SEMs) and a new software package for automated analysis of gunshot residues (GSR). The new GSR S50 and GSR F50 SEMs include the newly-released Magnum GSR software and specially-modified hardware to provide fully-automated analysis.

Brain Differences Between Species Identified

Oct 19 | News

New tools are enabling researchers to identify neural similarities and differences between species. The findings may help to explain faculties, like language, and diseases, like Parkinson’s, that are unique to humans.

Brain Research Explores Intersection of Male Biology and Behavior

Oct 19 | News

Scientists presented research on the spectrum of male behavior, physiology, and susceptibility to disease. In particular, new findings provide a better understanding of the full range of male behavior, from fatherhood, nurturing, and fairness on the one hand, to aggression, selfishness, and dominance on the other.

New Research Helps Therapies Get Around, Through Blood-Brain Barrier

Oct 19 | News

New findings show scientists are developing novel ways to bypass the blood-brain barrier (BBB), a network of blood vessels that prevents more than 95 percent of all chemicals from entering the brain from the bloodstream.

New Studies Show Benefits of Exercise on the Brain and Body

Oct 19 | News

New research focuses on the effects of physical activity on brain health and, more specifically, underscores the positive influence of regular physical activity on Parkinson’s disease, depression, premenstrual syndrome, and memory.

Estimating Black Hole Masses in Triaxial Galaxies

Oct 16 | PubGet

Most of the super massive black hole mass estimates based on stellar kinematics use the assumption that galaxies are axisymmetric oblate spheroids or spherical. Here we use fully general triaxial orbit-based models to explore the effect of relaxing the axisymmetric assumption on the previously...

Dynamical Model of Coherent Pion Production in Neutrino-Nucleus Scattering

Oct 16 | PubGet

We study coherent pion production in neutrino-nucleus scattering in the energy region relevant to neutrino oscillation experiments of current interest. Our approach is based on a combined use of the Sato-Lee model of electroweak pion production on a nucleon and the Delta-hole model of...

Significance of neutrino cross-sections for astrophysics

Oct 16 | PubGet

The heavens are full of neutrinos, but so far we have observed a small subset of those. Performing such observations and analyzing the data from them require a thorough understanding of neutrino interactions. In this short review, the current theoretical status of neutrino cross sections are...

Research Exchange

Meeting the Challenges of Long-term Time-lapse Imaging

Oct 26

Recent technological developments in the sequence capture of cellular events through a light microscope can be combined to image multiple independent experiments automatically, with many advantages.

Handle With Care

Aug 26

Researchers face the dual challenges of difficult to handle and hard to maintain stem cells.

Six Tips for More Successful Cell Cultures

Aug 18

For those who perform cell culture experiments, it pays to be meticulous. Even seemingly minor handling techniques and lab equipment features can make a difference in achieving success.

Rapid Generation of Assay-ready Serial Dilution Plates Using Two-stage Low Volume Pipetting

Jul 22

Researchers see the benefits of streamlining accurate serial dilution of stock solutions of compounds. By Joby Jenkins, TTP LabTech As the cost of drug development escalates there is a growing requirement to accelerate the R&D cycle and eliminate unwanted off-target drug effects earlier.

The Future of the FDA: Operating in an Electronic World

Oct 12

Acording to an Axendia reseach study, the FDA is currently shifting its organizational and technology infrastructures to facilitate electronic interactions with the companies it regulates.

Tissue Microarrays - Opening up new opportunities in the Therapeutics sector

Oct 12

Tissue Microarray has become a pivotal cog in the wheel for high throughput studies and is an integral part in the validation process for screening results from discovery platforms for expression studies using various approaches.

Translational Informatics for Systems Biology

Oct 12

A study in which IO Informatics' Sentient software has been applied to integrating and linking a customer's multiple data streams.

De Novo Formula Generation with Sub-ppm Confidence

Oct 12

Novel technology embodied in the micrOTOF allows precise measurement of both accurate mass and True Isotopic Pattern (TIP) over a wide dynamic range, allowing for the implementation of an open access system.

ADP-Glo™: An Ideal Approach to Monitor the Activity of Protein Kinases and Beyond

Oct 16

Because of its versatility (alltypesofsubstrates), robustness (Z’>0.8), rapidperformance, and its ease of use, the luminescence based Kinase Glo® assay platform has gained wide acceptance in many drug screening programs for protein kinase inhibitors.

A Cell-Based, Microplate Format, DELFIA Assay for Determination of the Activation of MAP KinaseSofia

Oct 16

Mitogen-activated protein kinases(MAPK) are activated in response to extracellularsignals or cellular stress. We have set up a cell-based DELFIA®Time-Resolved Fluorescence assay to test compounds or conditions for their ability to modulate cellular stress by the activation of MAPK.

Cell Based Assays for Studying the Effects of Cytotoxic Agents

Oct 16

Apoptosis, DNA fragmentation and cell proliferation are important parameters when studying live cell function, especially, when the effects of cytotoxic agents are under study.

Household characteristics associated with handwashing with soap in rural bangladesh.

4 hours ago

Handwashing with soap prevents diarrhea and respiratory disease, but it is rarely practiced in high-need settings. Among 100 randomly selected villages in rural Bangladesh, field workers enrolled 10 households per village and observed and recorded household activities for 5 hours....

Seasonal Pattern of Pneumonia Mortality among Under-Five Children in Nairobi's Informal Settlements.

7 hours ago

Using longitudinal data from the Nairobi Urban and Demographic Surveillance System (NUHDSS), we examined the seasonal pattern of pneumonia mortality among under-five children living in Nairobi's slums. We included 17,787 under-five children resident in the NUHDSS from January 1,...

A simplified, low-cost method for polarized light microscopy.

7 hours ago

Malaria pigment is an intracellular inclusion body that appears in blood and tissue specimens on microscopic examination and can help in establishing the diagnosis of malaria. In simple light microscopy, it can be difficult to discern from cellular background and artifacts. It has...

Request for Entries

Oct 16

Ask the Experts is your chance to get the answers to questions on applications, materials, methods, processes, and technologies. Email you question to bst_web@advantagemedia.com, and the editors of Bioscience Technology will find an appropriate expert to answer it. Watch this space in the future to see the questions your colleagues are posting.

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Video:

Frontiers in Bioscience Learning and Memory Video

Oct 6

How does the brain learn and remember? An academic conference "Frontiers in Bioscience Learning and Memory" was held at City University of Hong Kong on June 16th.

Podcasts:

Allen Institute for Brain Research

Allen Institute for Brain Research

Oct 14

Discussed in this interview are both the mouse brain project and the human cortex project with an emphasis on the importance of these projects to neuroscience research.