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10 Tips for Successful Sample Concentration and Buffer Exchange
Nov 6 2009 | Application Notes
Centrifugal devices with ultrafiltration (UF) membrane can solve common problems researchers face when working with proteins.
Publishing Data That Conform to the MIQE Guidelines
Jan 22 | Application Notes
Minimum information for publication of Quantitative Real-Time PCR Experiments (MIQE) guidelines help researchers design qPCR experiments.
Advances in EMCCD Technology: Making Imaging Less Arbitrary
Nov 16 2009 | Application Notes
Recent advances in EMCCD technology have solved the problem of non-standardized measurement units by using the photoelectron to standardize imaging experiments.
Meeting the Challenges of Long-term Time-lapse Imaging
Oct 26 2009 | Application Notes
Recent technological developments in the sequence capture of cellular events through a light microscope can be combined to image multiple independent experiments automatically, with many advantages.
Handle With Care
Aug 26 2009 | Application Notes
Researchers face the dual challenges of difficult to handle and hard to maintain stem cells.
Rapid Generation of Assay-ready Serial Dilution Plates Using Two-stage Low Volume Pipetting
Jul 22 2009 | Application Notes
Researchers see the benefits of streamlining accurate serial dilution of stock solutions of compounds. By Joby Jenkins, TTP LabTech As the cost of drug development escalates there is a growing requirement to accelerate the R&D cycle and eliminate unwanted off-target drug effects earlier.
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Jan 22
Calibration Free Analysis to Measure the Concentration of Active Proteins
Nov 23 2009
An SPR-based method, Calibration Free Concentration Analysis can be used to accurately determine the concentration of active protein in a sample, relating to the specific binding activity of the protein, and without the need for a standard.
Nov 16 2009
Nov 6 2009
more APPLICATION NOTES >>
Advantages of Monolithic Laser Combiner Technology in Confocal Microscopy Systems
Jan 6
Fluorescence microscopy techniques require a reliable light source at the desired wavelength or wavelengths, with minimal downtime for maintenance and alignment. Lasers are a popular light source, although the alignment and upkeep of laser combiners is a time-consuming prospect for many users.
Size-Exclusion Chromatography for Purification of Biomolecules
Dec 2 2009
Size-exclusion chromatography (SEC) is a popular method to separate biomolecules based on their size. Primarily, it is applied to the separation of biopolymers such as proteins and nucleic acids, i.e. water-soluble polymers.
Improving Separation During Electrophoresis
SeparateIT gels represent a novel gel matrix for DNA electrophoresis. Gel polymers are arranged in a conceptually different way, in accordance with a new theoretical model of gel electrophoresis.
Improving Quality of ELISA
Using ready-to-use ELISA kits from manufacturers is easy and convenient. Sometimes however, home-made ELISA is required because there is no kit available with the right antibodies or the characteristics of the available kits such as their limits of detection are not appropriate.
more WHITE PAPERS >>
Attention Deficit & Hyperactivity in a Drosophila Memory Mutant
Nov 9 2009
Action selection is modulated by external stimuli either directly or via memory retrieval. In a constantly changing environment, animals have evolved attention-like processes to effectively filter the incoming sensory stream. These attention-like processes, in turn, are modulated by memory. The neurobiological nature of how attention, action selection and memory are inter-connected is unknown. We describe here new phenotypes of the memory mutant radish in the fruit fly Drosophila.
Mechanisms of plasticity in simple taxis behaviors in Drosophila
Nov 8 2009
Like the proverbial moth drawn to the candle flame, the fruit fly Drosophila also stereotypically approaches light sources. This positive phototaxis is the archetypal example of hard-wired input-output behaviors.
Live cell imaging of mutant and wild-type GABA-A receptor trafficking using a novel reporter protein
Efficient signaling in the brain requires precise regulation and targeting of cell surface ion-channels. Mutations in these channels associated with inherited diseases can cause improper targeting and reduced surface expression.
ADP-Glo™: An Ideal Approach to Monitor the Activity of Protein Kinases and Beyond
Oct 16 2009
Because of its versatility (alltypesofsubstrates), robustness (Z’>0.8), rapidperformance, and its ease of use, the luminescence based Kinase Glo® assay platform has gained wide acceptance in many drug screening programs for protein kinase inhibitors.
more POSTERS >>
TCA cycle activity regulates tomato root growth via effects on secondary cell wall production
31 minutes ago
Simulating plant metabolic pathways with enzyme-kinetic models
Continuous turnover of carotenes and chlorophyll a in mature leaves of Arabidopsis thaliana revealed by 14CO2 pulse-chase labeling
SYSTEMS ANALYSIS OF SEED FILLING IN ARABIDOPSIS THALIANA: USING GENERAL LINEAR MODELING TO ASSESS CONCORDANCE OF TRANSCRIPT AND PROTEIN EXPRESSION
32 minutes ago
more JOURNAL ARTICLES >>
Prokariotic Cell Collection in Denmark
I would like to know about a prokariotic cell collection in Denmark. Is there a cell bank in this country? I need a Lactobacillus strain for a fermentation assay and this information about the bank is very helpful for me.
Request for Entries
Ask the Experts is your chance to get the answers to questions on applications, materials, methods, processes, and technologies. Email you question to bst_web@advantagemedia.com, and the editors of Bioscience Technology will find an appropriate expert to answer it. Watch this space in the future to see the questions your colleagues are posting.
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Zyprexa (olanzapine): Use in Adolescents
3 hours ago
Review and approval of oncology and hematology drugs at FDA from 2005 to 2007
9 hours ago
ConjuChem Biotechnologies reports $15.8M loss of latest financial year
Videx/Videx EC (didanosine): Labeling Revision - Risk of Non-Cirrhotic Portal Hypertension
10 hours ago
FDA Technical Briefing on Its FY 2011 Budget Request
Canadian earnings declared Friday: Norbord, Lorex, Sensio, Functional
SPRIworks Fragment Library System 1 From Beckman Coulter Genomics Wins New Product Award at LabAutomation2010
11 hours ago
more NEWS >>
Beckman Coulter Workstation Automates Antibody Cocktail Preparation
Jan 24 | News
Beckman Coulter Adds Streptamer* Technology To Cell-Sorting, Cell-Characterizing Lines
Jan 22 | News
Beckman Coulter Genomics and the J. Craig Venter Institute Collaborate on Validation of the SPRIworks Fragment Library System I for the Illumina Genome Analyzer
Jan 8 | News
Gilson releases the new FTLC System
Jan 3 | News
Millipore Hosts Web Seminar on Risk Assessment of Extractables & Leachables from Single-Use Systems
Carl Zeiss and UCalifornia, San Francisco Agree on Marketing Rights for Superresolution Microscopy Techniques
Dec 29 2009 | News
Dr. Robert Langer Joins Millipore’s Board of Directors
Dec 18 2009 | News
more SUPPLIER UPDATES >>
Oct 26 2009
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Neuroscience Diseases of The Brain and How The Mind Emerges
Dennis Choi, director of Emory Universitys Neuroscience Center, is renowned for his groundbreaking research on brain and spinal cord injury.
more VIDEO >>
Allen Institute for Brain Research
Oct 14 2009
Discussed in this interview are both the mouse brain project and the human cortex project with an emphasis on the importance of these projects to neuroscience research.
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