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Publishing Data That Conform to the MIQE Guidelines
Jan 22
Minimum information for publication of Quantitative Real-Time PCR Experiments (MIQE) guidelines help researchers design qPCR experiments.
Calibration Free Analysis to Measure the Concentration of Active Proteins
Nov 23 2009
An SPR-based method, Calibration Free Concentration Analysis can be used to accurately determine the concentration of active protein in a sample, relating to the specific binding activity of the protein, and without the need for a standard.
Advances in EMCCD Technology: Making Imaging Less Arbitrary
Nov 16 2009
Recent advances in EMCCD technology have solved the problem of non-standardized measurement units by using the photoelectron to standardize imaging experiments.
10 Tips for Successful Sample Concentration and Buffer Exchange
Nov 6 2009
Centrifugal devices with ultrafiltration (UF) membrane can solve common problems researchers face when working with proteins.
more APPLICATION NOTES >>
Advantages of Monolithic Laser Combiner Technology in Confocal Microscopy Systems
Jan 6
Fluorescence microscopy techniques require a reliable light source at the desired wavelength or wavelengths, with minimal downtime for maintenance and alignment. Lasers are a popular light source, although the alignment and upkeep of laser combiners is a time-consuming prospect for many users.
Size-Exclusion Chromatography for Purification of Biomolecules
Dec 2 2009
Size-exclusion chromatography (SEC) is a popular method to separate biomolecules based on their size. Primarily, it is applied to the separation of biopolymers such as proteins and nucleic acids, i.e. water-soluble polymers.
Improving Separation During Electrophoresis
SeparateIT gels represent a novel gel matrix for DNA electrophoresis. Gel polymers are arranged in a conceptually different way, in accordance with a new theoretical model of gel electrophoresis.
Improving Quality of ELISA
Using ready-to-use ELISA kits from manufacturers is easy and convenient. Sometimes however, home-made ELISA is required because there is no kit available with the right antibodies or the characteristics of the available kits such as their limits of detection are not appropriate.
more WHITE PAPERS >>
Ensuring Quality in Assays Performed with Automated Liquid Handlers
Feb 2
The focus of this presentation is to highlight the need of ensuring quality in important assays performed with automated liquid handlers. Nearly all assays performed within a laboratory are volume-dependent. In turn, all concentrations of biological and chemical components in these assays, as well as the associated dilution protocols, are volume-dependent. Because analyte concentration is volume-dependent, an assay’s results might be falsely interpreted if liquid handler variability and inaccuracies are unknown or if the system(s) go unchecked for a long period.
Inkjet System for Protein Crystallography
Feb 1
X-ray crystallography is used routinely by scientists to obtain the three dimensional structure of a biological molecule of interest.Such information can be used to determine how a pharmaceutical interacts with a protein target and what changes might improve functionality. However, the crystallization of macromolecules still remains a serious hindrance in structural determination despite impressive advances in screening methods and technologies.
Attention Deficit & Hyperactivity in a Drosophila Memory Mutant
Nov 9 2009
Action selection is modulated by external stimuli either directly or via memory retrieval. In a constantly changing environment, animals have evolved attention-like processes to effectively filter the incoming sensory stream. These attention-like processes, in turn, are modulated by memory. The neurobiological nature of how attention, action selection and memory are inter-connected is unknown. We describe here new phenotypes of the memory mutant radish in the fruit fly Drosophila.
Mechanisms of plasticity in simple taxis behaviors in Drosophila
Nov 8 2009
Like the proverbial moth drawn to the candle flame, the fruit fly Drosophila also stereotypically approaches light sources. This positive phototaxis is the archetypal example of hard-wired input-output behaviors.
more POSTERS >>
What price access to the open seas? The geopolitics of oil and gas transmission from the Trans-Caspian republics
Feb 16
In the late 1980s, the Soviet Union was the world's largest hydrocarbon producer. The landmass over which these resources are distributed is vast and the reserves mostly landlocked. To convey these hydrocarbons to refineries and to market, the Soviets constructed the largest...
Is Los Angeles-Style Sprawl Desirable?
This article reviews the literature on characteristics, causes, and costs of alternative development patterns. In doing so it debunks arguments by Gordon and Richardson in favor of Los Angeles-style sprawl. Sprawl is not suburbanization generally, but rather forms of suburban...
Cow preference and usage of free stalls compared with an open pack area.
Free-stall housing systems are designed to provide a comfortable and hygienic lying area, but some aspects of stall design may restrict usage by cows. The aim of this study was to compare free-stall housing with a comparable lying area (open pack) without stall...
Palaeoecological interpretations of South Australian Precambrian stromatolites
Despite the palaeoecological emphasis of recent stromatolite research outside the USSR, controversy still exists regarding the environmental restriction of these organosedimentary structures and some analogies with modern occurrences have been maintained too rigidly....
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Prokariotic Cell Collection in Denmark
I would like to know about a prokariotic cell collection in Denmark. Is there a cell bank in this country? I need a Lactobacillus strain for a fermentation assay and this information about the bank is very helpful for me.
Request for Entries
Oct 16 2009
Ask the Experts is your chance to get the answers to questions on applications, materials, methods, processes, and technologies. Email you question to bst_web@advantagemedia.com, and the editors of Bioscience Technology will find an appropriate expert to answer it. Watch this space in the future to see the questions your colleagues are posting.
more ASK THE EXPERTS >>
Novavax presents swine flu vaccine data
49 minutes ago
Booker Prize winner gives exclusive taster of latest novel
3 hours ago
Manchester leads green chemical push
4 hours ago
Rise of sexual predators in energy boomtowns highlights social problems
8 hours ago
Potential Signals of Serious Risks/New Safety Information Identified from the Adverse Event Reporting System (AERS) between October - December 2008
13 hours ago
Potential Signals of Serious Risks/New Safety Information Identified from the Adverse Event Reporting System (AERS) between April - June 2008
Potential Signals of Serious Risks/New Safety Information Identified from the Adverse Event Reporting System (AERS) between January - March 2008
more NEWS >>
Gilson, Inc. Strategic Partnership for Mass Spectrometry - 2/2/2024
Feb 10 | News
Millipore Joins Biomedical Diagnostics Institute
Beckman Coulter to Distribute CellaVision Products in the U.S.
Feb 4 | News
Millipore Delivers Outstanding 2009 Financial Results
Feb 3 | News
Beckman Coulter Genomics Partners with Genpathway to Offer Comprehensive ChIP-Seq Solutions
Feb 2 | News
Beckman Coulter Workstation Automates Antibody Cocktail Preparation
Jan 24 | News
Beckman Coulter Adds Streptamer* Technology To Cell-Sorting, Cell-Characterizing Lines
Jan 22 | News
more SUPPLIER UPDATES >>
Poised Transcription Factories Prime Silent uPA Gene Prior to Activation
Feb 10
A toolkit for the characterization of CCD cameras for transmission electron microscopy.
Quantification and cluster analysis of actin cytoskeletal structures in plant cells: role of actin bundling in stomatal movement during diurnal cycles in Arabidopsis guard cel...
Recovery Act Funds Expand Studies of Stem Cell Biology
JCI online early table of contents: Feb. 15, 2010
Feb 15
UCLA study reveals how genes interact with their environment to cause disease
19 hours ago | News
VARI findings may help patients with deadly kidney cancer
21 hours ago | News
AGA offers new recommendations for CRC surveillance for certain patients with IBD
Feb 16 | News
Feb 15 | News
New therapeutic target for most common solid cancer in childhood?
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Neuroscience Diseases of The Brain and How The Mind Emerges
Dennis Choi, director of Emory Universitys Neuroscience Center, is renowned for his groundbreaking research on brain and spinal cord injury.
more VIDEO >>
Allen Institute for Brain Research
Oct 14 2009
Discussed in this interview are both the mouse brain project and the human cortex project with an emphasis on the importance of these projects to neuroscience research.
more PODCASTS >>