HPLC Column Addresses Difficult-to-Resolve Compounds

Phenomenex introduces the Kinetex C8 5-micron core-shell HPLC column. The used C8 phase delivers retention for the analysis of hydrophobic and “sticky” compounds. In combination with Kinetex Core-Shell Technology, this phase gives analysts a high-performance reversed phase alternative for HPLC methods. As with the existing Kinetex 5-micron C18 and XB-C18 phases, the new 5-micron C8 core-shell column can be substituted into methods that meet United States Pharmacopeia (USP) and European Pharmacopoeia (Ph. Eur.) requirements. Specifically the Kinetex 5-micron C8 meets USP specifications for Classification Code L7, enabling laboratories using 5-micron L7 columns to realize the performance benefits of Kinetex Core-Shell Technology without adjusting their USP methodology. According to the company, Kinetex 5-micron core-shell media, the largest diameter particle in the family, delivers better performance than 3 and 5-micron fully porous offerings, with no increase in backpressure, and the new 5-micron media provides 90 percent higher average efficiencies compared to the same size fully porous columns with little to no method development. Kinetex 5-micron C8 columns are fully scalable to or from the 1.7- and 2.6-micron particles, enabling easy method transferability.

Phenomenex Inc., 310-212-0555, www.phenomenex.com