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Cyclotrons could alleviate medical isotope shortage

(Society of Nuclear Medicine) The most widely used medical radioisotope, Technetium-99m (Tc-99m), is essential for an estimated 70,000 medical imaging procedures that take place daily around the world. Aging reactors, production intermittencies and threats of permanent reactor...

Targeted radioisotope generator could be used for molecular imaging

(Society of Nuclear Medicine) According to a study presented at SNM's 57th Annual Meeting, a new radioisotope generator could enhance images produced by a molecular imaging technique known as positron emission tomography.

Radioactive optical imaging and 'quantum dot' nano-imaging at the forefront of molecular medicine

(Society of Nuclear Medicine) During SNM's 57th Annual Meeting, investigators presented the results of a multidisciplinary study involving the capture of radiation luminescence and radioactive-excited nanoparticles to help detect subtle signs of disease.

Detecting tumors faster

(Fraunhofer-Gesellschaft) To diagnose cancer reliably, doctors usually conduct a biopsy including tissue analysis -- which is a time-consuming process. A microscopic image sensor, fitted in an endoscope, is being developed for in vivo cancer diagnosis, to speed up the detection of tumors.

AFOSR initiates Russian and US scientists' collaboration in plasma aerodynamics

(Air Force Office of Scientific Research) Scientists from the US and Russia, engaged in a unique collaboration organized by the Air Force Office of Scientific Research, are conducting research in high-speed wind tunnel facilities to make discoveries in plasma-assisted combustion...

Taking the guesswork out of soil classification

(University of Missouri-Columbia) A University of Missouri doctoral student has developed a technique that uses digital imaging of soil samples to take some of the guesswork out of wetland identification.

OSA to host energy meetings in Tucson covering optics' role in alternative energy

(Optical Society of America) The Optical Society (OSA) today announced that it will host two energy meetings in Tucson: the Imaging and Applied Optics Congress, June 7-8, at the Westin La Paloma, and the Optical Interference Coatings Topical Meeting, June 6-11, at the Loews Ventana...

Study is first to find that CPAP therapy restores brain tissue in adults with sleep apnea

(American Academy of Sleep Medicine) Obstructive sleep apnea patients had reductions of gray-matter volume at baseline but showed significant gray-matter volume increase after three months of CPAP therapy. No further improvement in gray-matter volume was observed after one year of...

Applied nuclear physics for biomedicine, nuclear security and basic science

(DOE/Lawrence Berkeley National Laboratory) The Applied Nuclear Physics program in Lawrence Berkeley National Laboratory's Nuclear Science Division takes equipment created for basic research and develops it into tools that can address practical needs like cancer therapy and...

Scientists capture secret dance of electrons that causes them to change form

(McMaster University) Scientists have captured the first images of electrons that appear to take on extraordinary mass under certain extreme conditions, thus solving a 25-year mystery about how electrons behave in metals. The discovery could help with the design of new materials...

Research Exchange

Optical Imaging in Stem Cell Research

Jun 1

Developing sensitive, non-invasive technologies to monitor engraftment in vivo is essential to accelerate the clinical implementation of cell therapies.

Standing Up in a Court of Law

Jun 1

Private forensic testing laboratory ensures data integrity with advanced calibration systems.

Simultaneous Measurement of Multiple Signaling Pathways in Human Leukemias Using Flow Cytometry

May 24

Next generation assays will need to be robust and standardized in order to make the transition from a research procedure to a routine clinical assay. Flow cytometry provides a unique and sensitive method to accomplish these requirements.

Automated Forensic DNA Methods: Relieving the Pain of Validation

Apr 21

Automation can increase a forensics lab's sample processing capacity, but it can also add to the complexity of system verification and validation.

Step up to the MIQE

Mar 30

Over the years, polymerase chain reaction (PCR) has evolved into a readily automated, high throughput quantitative technology. Real-time quantitative PCR (qPCR) has become the industry standard for the detection and quantification of nucleic acids for multiple application, including quantification of RNA levels. But a lack of consensus among researchers on how to best perform and interpret qPCR experiments presents a major hurdle for advancement of the technology. This problem is exacerbated by insufficient experimental detail in published work, which impedes the ability of others to accurately evaluate or replicate reported results.

Fast Optimization of a Multiplex Influenza Identification Panel Using a Thermal Gradient

Mar 30

The year 2009 was marked by the emergence of a novel influenza A (H1N1) virus that infects humans. There is a need to identify the different strains of influenza virus for purposes of monitoring the H1N1 strain pandemic and for other epidemiological and scientific purposes.

Advantages of Monolithic Laser Combiner Technology in Confocal Microscopy Systems

Jan 6

Fluorescence microscopy techniques require a reliable light source at the desired wavelength or wavelengths, with minimal downtime for maintenance and alignment. Lasers are a popular light source, although the alignment and upkeep of laser combiners is a time-consuming prospect for many users.

Size-Exclusion Chromatography for Purification of Biomolecules

Dec 2 2009

Size-exclusion chromatography (SEC) is a popular method to separate biomolecules based on their size. Primarily, it is applied to the separation of biopolymers such as proteins and nucleic acids, i.e. water-soluble polymers.

Using the Tecan Genesis Workstation to Automate a Cytometric Bead Array (CBA) Immunoassay

Mar 11

The poster describe the process involved in automating a Cytometric Bead Array (CBA) immunoassay developed to measure relative concentrations of serum antibodies against Tetanus (TT), Sperm Whale Myoglobin (SWM) and Keyhole Limpet Hemocyanin (KLH) in KLH-immunized volunteers.

Ensuring Quality in Assays Performed with Automated Liquid Handlers

Feb 2

The focus of this presentation is to highlight the need of ensuring quality in important assays performed with automated liquid handlers. Nearly all assays performed within a laboratory are volume-dependent. In turn, all concentrations of biological and chemical components in these assays, as well as the associated dilution protocols, are volume-dependent. Because analyte concentration is volume-dependent, an assay’s results might be falsely interpreted if liquid handler variability and inaccuracies are unknown or if the system(s) go unchecked for a long period.

Inkjet System for Protein Crystallography

Feb 1

X-ray crystallography is used routinely by scientists to obtain the three dimensional structure of a biological molecule of interest.Such information can be used to determine how a pharmaceutical interacts with a protein target and what changes might improve functionality. However, the crystallization of macromolecules still remains a serious hindrance in structural determination despite impressive advances in screening methods and technologies.

Attention Deficit & Hyperactivity in a Drosophila Memory Mutant

Attention Deficit & Hyperactivity in a Drosophila Memory Mutant

Nov 9 2009

Action selection is modulated by external stimuli either directly or via memory retrieval. In a constantly changing environment, animals have evolved attention-like processes to effectively filter the incoming sensory stream. These attention-like processes, in turn, are modulated by memory. The neurobiological nature of how attention, action selection and memory are inter-connected is unknown. We describe here new phenotypes of the memory mutant radish in the fruit fly Drosophila.

Prokariotic Cell Collection in Denmark

Nov 6 2009

I would like to know about a prokariotic cell collection in Denmark. Is there a cell bank in this country? I need a Lactobacillus strain for a fermentation assay and this information about the bank is very helpful for me.

Request for Entries

Oct 16 2009

Ask the Experts is your chance to get the answers to questions on applications, materials, methods, processes, and technologies. Email you question to bst_web@advantagemedia.com, and the editors of Bioscience Technology will find an appropriate expert to answer it. Watch this space in the future to see the questions your colleagues are posting.

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Video:

Neuroscience Diseases of The Brain and How The Mind Emerges

Neuroscience Diseases of The Brain and How The Mind Emerges

Nov 8 2009

Dennis Choi, director of Emory Universitys Neuroscience Center, is renowned for his groundbreaking research on brain and spinal cord injury.

Podcasts:

Allen Institute for Brain Research

Allen Institute for Brain Research

Oct 14 2009

Discussed in this interview are both the mouse brain project and the human cortex project with an emphasis on the importance of these projects to neuroscience research.

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